HT5014

Formalin solution, neutral buffered, 10%

Name: Formalin solution, neutral buffered, 10%
Brand: SIGMA

case of 24 × 120 mL, histological tissue fixative

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About This Item

UNSPSC Code:

12352114

PubChem Substance ID:

24895890

NACRES:

NA.47

MDL number:

MFCD00003274

Key Documents

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InChI

1S/CH2O/c1-2/h1H2

SMILES string

[O-]#[C+H2]

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

packaging

case of 24 × 120 mL

concentration

10% formalin (approx. 4% formaldehyde)

color

colorless

pH

6.90-7.10

density

1.080 g/cm³

application(s)

hematology
histology

storage temp.

room temp

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Application

Formalin solution, neutral buffered, 10% has been used to fix skin samples, tumor samples and HepG2 human liver carcinoma cells.[1][2]

Popular general purpose histological fixative.

Packaging

Case containers are polypropylene with white leak-proof lids and are partially prefilled with 10% NBF.

Physical form

Neutral buffered solution

pictograms

GHS08,GHS07

signalword

Danger

hcodes

H302 + H332,H317,H341,H350

pcodes

P202 - P280 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P308 + P313

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Skin Sens. 1

wgk

WGK 3

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

50-00-0 + 67-56-1

CAS No.

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Cyclin D3 deficiency inhibits skin tumor development, but does not affect normal keratinocyte proliferation.

Lee S H, et al.

Oncology Letters, 14(3), 2723-2734 (2017)

Delaying implant-based mammary reconstruction after radiotherapy does not decrease capsular contracture: An in vitro study.

Mostafa El-Diwany et al.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 70(9), 1210-1217 (2017-07-09)

The most common complications of irradiated implant-based mammary reconstruction are fibrosis and capsular contracture. The indications for postmastectomy adjuvant radiotherapy have considerably broadened. Facing an increased number of patients who will require radiotherapy, most guidelines recommend delaying reconstruction after radiotherapy

Catalase inhibition induces pexophagy through ROS accumulation.

Lee J N, et al.

Biochemical and Biophysical Research Communications, 501(3), 696-702 (2018)

Massive transcriptome sequencing of human spinal cord tissues provides new insights into motor neuron degeneration in ALS.

Anna Maria D'Erchia et al.

Scientific reports, 7(1), 10046-10046 (2017-09-01)

ALS is a devastating and debilitating human disease characterized by the progressive death of upper and lower motor neurons. Although much effort has been made to elucidate molecular determinants underlying the onset and progression of the disorder, the causes of

Expression level and subcellular localization of heme oxygenase-1 modulates its cytoprotective properties in response to lung injury: a mouse model.

Fumihiko Namba et al.

PloS one, 9(3), e90936-e90936 (2014-03-07)

Premature infants exposed to hyperoxia suffer acute and long-term pulmonary consequences. Nevertheless, neonates survive hyperoxia better than adults. The factors contributing to neonatal hyperoxic tolerance are not fully elucidated. In contrast to adults, heme oxygenase (HO)-1, an endoplasmic reticulum (ER)-anchored

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