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H9414

Halofantrine hydrochloride

≥98% (HPLC), HERG channel blocker, solid

Synonym(s):

1,3-Dichloro-a-[2-(dibutylamino)ethyl]-6-(trifluoromethyl)-9-phenanthrenemethanol hydrochloride, Halfan

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10 mg
Please contact Customer Service for Availability
CZK 4,030.00
CZK 3,425.50
50 mg
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CZK 16,100.00

About This Item

Empirical Formula (Hill Notation):
C26H30Cl2F3NO · HCl
CAS Number:
36167-63-2
Molecular Weight:
536.88
NACRES:
NA.77
PubChem Substance ID:
329815264
UNSPSC Code:
12352200
EC Number:
252-895-4
MDL number:
MFCD00879136
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated

CZK 3,425.50

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Product Name

Halofantrine hydrochloride, ≥98% (HPLC), solid

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

color

white to off-white

solubility

DMSO: >10 mg/mL

originator

GlaxoSmithKline

storage temp.

2-8°C

SMILES string

Cl.CCCCN(CCCC)CCC(O)c1cc2c(Cl)cc(Cl)cc2c3cc(ccc13)C(F)(F)F

InChI

1S/C26H30Cl2F3NO.ClH/c1-3-5-10-32(11-6-4-2)12-9-25(33)23-16-22-21(14-18(27)15-24(22)28)20-13-17(26(29,30)31)7-8-19(20)23;/h7-8,13-16,25,33H,3-6,9-12H2,1-2H3;1H

InChI key

WANGFTDWOFGECH-UHFFFAOYSA-N

Biochem/physiol Actions

Halofantrine is a blocker of delayed rectifier potassium current via the inhibition of hERG channel.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Halofantrine hydrochloride ≥98% (HPLC), solid

Sigma-Aldrich

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Halofantrine hydrochloride

(±)-Bufuralol hydrochloride

Sigma-Aldrich

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(±)-Bufuralol hydrochloride

Xaliproden hydrochloride ≥97% (HPLC), solid

Sigma-Aldrich

X4879

Xaliproden hydrochloride

Aprindine hydrochloride ≥98% (HPLC), solid

Sigma-Aldrich

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Aprindine hydrochloride

form

solid

form

solid

form

solid

form

solid

assay

≥98% (HPLC)

assay

-

assay

≥97% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

desiccated

solubility

DMSO: >10 mg/mL

solubility

H2O: soluble, methanol: soluble

solubility

DMSO: ≥5 mg/mL

solubility

H2O: >10 mg/mL

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hcodes

H413

Hazard Classifications

Aquatic Chronic 4

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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