G8294

Anti-Gonadotropin Releasing Hormone (GnRH) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• UNSPSC Code: 12352203
• MDL number: MFCD02096474
• Conjugate: unconjugated
• Clone: polyclonal
• Application: IHC
• Citations: 17

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: mouse
• technique(s): immunohistochemistry: 1 μg/mL using mouse embryo brain
• UniProt accession no.: P13562
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... GNRH1(2796) ; mouse ... Gnrh1(14714) ; rat ... Gnrh1(25194)

Description

Immunogen

synthetic peptide pyroEHWSYGLRP(G-NH₂) corresponding to human GnRH. The sequence is completely conserved in rat and tree shrew and 78% conserved in zebrafish.

Application

Anti-Gonadotropin Releasing Hormone (GnRH) antibody produced in rabbit is suitable for immunoprecipitation of GnRH purified from adult amphioxus tissues. It is suitable for immunohistochemistry at a working concentration of 1μg/mL using mouse embryo brain.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)

Biochem/physiol Actions

Gonadotropin releasing hormone (GnRH) is crucial for the regulation of reproduction in vertebrates. It is a decapeptide and is expressed by neurons in the medial basal hypothalamus (MBH) and secreted in a pulsatile manner into the cardiovascular system. Neural, hormonal and environmental stimuli affect the generation of GnRH pulses, which in turn affect the secretion of follicle stimulating hormone(FSH) and luteinizing hormone (LH) from the pituitary. It may be involved in mediating cancers of the reproductive system.

Physical form

Solution in phosphate buffered saline containing 1.0 mg/mL bovine serum albumin and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable