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Glycine

Name: Glycine
Brand: SIGMA
Price: 4350 CZK

≥99% (titration), suitable for electron microscopy, BioXtra

Synonym(s):

Aminoacetic acid, Aminoethanoic acid, Glycocoll

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Size/SKU	Availability	Price
100 g	Please contact Customer Service for Availability	4 350,00 CZK
250 g	Please contact Customer Service for Availability	7 740,00 CZK
1 kg	Please contact Customer Service for Availability	22 600,00 CZK

About This Item

Linear Formula:

NH₂CH₂COOH

CAS Number:

56-40-6

Molecular Weight:

75.07

NACRES:

NA.26

PubChem Substance ID:

24895306

eCl@ss:

32160406

UNSPSC Code:

12352209

EC Number:

200-272-2

MDL number:

MFCD00008131

Beilstein/REAXYS Number:

635782

4 350,00 CZK

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Properties

Product Name

Glycine, BioXtra, ≥99% (titration)

product line

BioXtra

Quality Segment

200

assay

≥99% (titration)

form

powder

technique(s)

electron microscopy: suitable

impurities

Insoluble matter, passes filter test

ign. residue

≤0.05%

loss

≤0.05% loss on drying, HV, 20-26 °C

color

white

pKa (25 °C)

(1) 2.35, (2) 9.60, 2.35

mp

240 °C (dec.) (lit.)

solubility

1 M HCl: 1 M, clear, colorless

anion traces

chloride (Cl^-): ≤0.005%, sulfate (SO₄^2-): ≤0.005%

cation traces

Al: ≤0.0005%, As: ≤0.00001%, Ba: ≤0.0005%, Bi: ≤0.0005%, Ca: ≤0.001%, Cd: ≤0.0005%, Co: ≤0.0005%, Cr: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Li: ≤0.0005%, Mg: ≤0.0005%, Mn: ≤0.0005%, Mo: ≤0.0005%, NH₄⁺: ≤0.02%, Na: ≤0.02%, Ni: ≤0.0005%, Pb: ≤0.0005%, Sr: ≤0.0005%, Zn: ≤0.0005%

absorption

≤0.04 at 260 in 1 M HCl at 1 M, ≤0.04 at 280 in 1 M HCl at 1 M

SMILES string

NCC(O)=O

UV absorption

λ: 260 nm A_max: ≤0.04, λ: 260 nm A_max: 0.003, λ: 260 nm A_max: 0.006

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Gene Information

rat ... Grin2a(24409)

Description

Application

Glycine has been used to quench unreacted aldehyde during sample (nuclei) preparation for scanning electron microscope. It has also been used for sample fixation in the process of immunolabeling.

Biochem/physiol Actions

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

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This Item	15527	G7126	3570
Sigma-Aldrich G7403 Glycine	Sigma-Aldrich 15527 Glycine	Sigma-Aldrich G7126 Glycine	Millipore 3570 Glycine
description BioXtra, ≥99% (titration)	description meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)	description ReagentPlus^®, ≥99% (HPLC)	description -
form powder	form crystalline powder	form powder	form crystalline solid
technique(s) electron microscopy: suitable	technique(s) IR spectroscopy: suitable	technique(s) western blot: suitable	technique(s) -
assay ≥99% (titration)	assay 99-101% (based on anhydrous substance)	assay ≥99% (HPLC)	assay >99% (by assay)
product line BioXtra	product line -	product line ReagentPlus^®	product line -
cation traces Ni: ≤0.0005%, Li: ≤0.0005%, Bi: ≤0.0005%, Sr: ≤0.0005%, NH₄⁺: ≤0.02%, Cu: ≤0.0005%, Mg: ≤0.0005%, Zn: ≤0.0005%, K: ≤0.005%, Na: ≤0.02%, Ca: ≤0.001%, Pb: ≤0.0005%, As: ≤0.00001%, Al: ≤0.0005%, Co: ≤0.0005%, Cd: ≤0.0005%, Cr: ≤0.0005%, Mo: ≤0.0005%, Fe: ≤0.0005%, Ba: ≤0.0005%, Mn: ≤0.0005%	cation traces -	cation traces ≤0.01% (Ammonia (NH3))	cation traces heavy metals (as Pb): ≤5 ppm, Fe: ≤10 ppm
impurities Insoluble matter, passes filter test	impurities ≤1.0% ninhydrin-positive substances, organic volatile impurities, complies (GC), hydrolyzable substances, complies, residual solvents, complies, ≤0.001% heavy metals (as Pb)	impurities ≤0.01% Ammonia	impurities ≤6.0 EU/g Endotoxin, ≤100 CFU/g Total microorganism

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Storage Class

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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