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G1049

Poly-L-γ-glutamic acid sodium salt

suitable for drug transporter assays, Mol wt ≥750,000

Synonym(s):

γ-PGA

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Size/SKUAvailabilityPrice
100 mg
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CZK 7,180.00

About This Item

CAS Number:
MDL number:
NACRES:
NA.26
UNSPSC Code:
12352209

CZK 7,180.00


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Product Name

Poly-L-γ-glutamic acid sodium salt,

form

powder

Quality Segment

mol wt

≥750,000

technique(s)

drug transporter assay: suitable

color

white to off-white

application(s)

cell analysis

storage temp.

−20°C

Application

High molecular weight poly-γ-glutamic acid (γPGA) was found to increase levels of NK cell-mediated cytotoxicity and INF-γ secretion in C57BL/6 mice.[1] Biodegradable γ-PGA nanoparticles have been evaluated for use as antigen delivery carriers and delivery of influenza virus hemagglutin (HA) vaccine.[2] Additional life science applications for γ-PGA include uses in biodegradable fibers and nanofiber sheets, hydrogels, and cryoprotectants.[3][4]

Other Notes

High molecular weight poly-γ-glutamic acid is a polymer of glutamic acid connected by amide linkages between α-amino and γ-carboxylic acid groups. γ-PGA is produced by fermentation in Bacillus species. The subunits are predominantly L-isomer.

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This Item
G6503G6503B1758
form

powder

form

powder or chunks

form

powder or chunks

form

powder

technique(s)

drug transporter assay: suitable

technique(s)

drug transporter assay: suitable

technique(s)

drug transporter assay: suitable

technique(s)

drug transporter assay: suitable

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

-

storage temp.

−20°C

color

white to off-white

color

white

color

white

color

white to off-white

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

mol wt

≥750,000

mol wt

-

mol wt

-

mol wt

-


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Questions

1–4 of 4 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. What is the production strain of this product? Bacillus subtilis natto ATCC 15245? Bacillus paralicheniformis ATCC 9945a?

    1 answer
    1. The preparation and production of this product is considered proprietary.

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  4. Is G1049 product free of endotoxin? 

    1 answer
    1. Unfortunately, this product is not tested to determine endotoxin.

      Helpful?

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