F7057

Folate Receptor 2 human

recombinant, expressed in CHO cells, ≥95% (SDS-PAGE)

• Synonym(s): FOLR2, Folate Receptor beta
• NACRES: NA.56
• UNSPSC Code: 12352202
• Form: lyophilized
• Assay: ≥95% (SDS-PAGE)
• Biological source: human
• Recombinant: expressed in CHO cells

Properties

• biological source: human
• Quality Segment: 100
• recombinant: expressed in CHO cells
• assay: ≥95% (SDS-PAGE)
• form: lyophilized
• impurities: ≤1.0 EU/μg endotoxin
• UniProt accession no.: P14207
• application(s): cell analysis
• storage temp.: −20°C
• Gene Information: human ... FOLR2(2350)

Description

Application

Folate Receptor 2 has been used in studies of the treatment of rheumatoid arthritis (RA) with Methotrexate (MTX). These studies have focused on transport of MTX through folate receptor 2 in RA synovial macrophages.

Biochem/physiol Actions

Folate Receptor 2 is a 38kDa protein that has a high affinity for folic acid and mediates 5-methyltetrahydrofolate to the inside of the cell.

Physical form

Lyophilized from PBS

Preparation Note

Reconstitute at 100 μg/ mL in PBS

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable