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F5130

5-Fluorouridine

≥99% (HPLC), synthetic (organic), powder

1 of 1 reviewers received a sample product or took part in a promotion

Synonym(s):

5-Fluorouracil 1β-D-ribofuranoside, FUrd

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Size/SKUAvailabilityPrice
100 mg
Please contact Customer Service for Availability
3 170,00 CZK
250 mg
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9 410,00 CZK
7 998,50 CZK
1 g
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17 400,00 CZK

About This Item

Empirical Formula (Hill Notation):
C9H11FN2O6
CAS Number:
Molecular Weight:
262.19
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
206-260-3
MDL number:
Beilstein/REAXYS Number:
33662
Assay:
≥99% (HPLC)
Biological source:
synthetic (organic)
Form:
powder
Solubility:
water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

3 170,00 CZK


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Product Name

5-Fluorouridine, proapoptotic anitproliferative plant growth regulator

biological source

synthetic (organic)

Quality Segment

assay

≥99% (HPLC)

form

powder

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=C(F)C(=O)NC2=O

InChI

1S/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1

InChI key

FHIDNBAQOFJWCA-UAKXSSHOSA-N

General description

5-Fluorouridine (FUrd) is a fluoropyrimidine nucleoside analog and a cell-permeable modified RNA precursor.

Application

5-Fluorouridine has been used for labeling active transcription sites in the porcine fetal fibroblasts and human cell lines for immunocytochemistry analysis. It has also been used to monitor apoptosis during drug sensitivity assay in esophageal squamous cell carcinoma (ESCC) cells.

Biochem/physiol Actions

5-Fluorouridine (FUrd) is cytotoxic towards cancer cells. FUrd is often used in chemical and biochemical comparison studies with fluorouracil and thymine analogs.

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Show Differences

1 of 1

This Item
F0503343922G6752
description

proapoptotic anitproliferative plant growth regulator

description

thymidylate synthase inhibitor

description

Potent antitumor agent.

description

≥98%

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

-

biological source

microbial

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

200

form

powder

form

powder

form

solid

form

powder

assay

≥99% (HPLC)

assay

≥99% (HPLC)

assay

≥98% (HPLC)

assay

≥98%

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

solubility

DMSO: 5 mg/mL, DMF: 5 mg/mL, methanol: 1 mg/mL, hot water: 1 mg/mL

solubility

formic acid:water (1:1): 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves



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Questions

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    • Review 1
    • Votes 0
    2 out of 5 stars.

    Review of chemical compound

    This product is reasonably priced compared to other suppliers.

    Helpful?

    1. Response from Merck KGaA:

      Thank you for taking the time to leave a review! Our Customer Service department is available to discuss getting the best quality products for your needs at the right price. Please feel free to contact us by visiting https://www.sigmaaldrich.com/support/customer-support and submit a Product Pricing and Availability ticket. We look forward to hearing from you soon!