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2-Fluoro-2-deoxy-D-glucose

Name: 2-Fluoro-2-deoxy-<SC>D</SC>-glucose
Brand: SIGMA
Price: 11400 CZK
Availability: InStock

glycosylation inhibitor, glucose analog

Synonym(s):

2-Deoxy-2-fluoro-D-glucose, FDG, 2-Deoxy-2-fluoro-D-glucose

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Size/SKU	Availability	Price
25 mg	Available to ship TODAYfromSchnelldorf Distribution	11 400,00 CZK
100 mg	Available to ship TODAYfromSchnelldorf Distribution	34 800,00 CZK

About This Item

Empirical Formula (Hill Notation):

C₆H₁₁FO₅

CAS Number:

29702-43-0

Molecular Weight:

182.15

NACRES:

NA.32

PubChem Substance ID:

24894876

UNSPSC Code:

41116107

MDL number:

MFCD00077527

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Properties

Quality Segment

300

assay

≥98.00% (TLC)

form

powder

mol wt

182.15 g/mol

concentration

≤100% (2-Fluoro-2-deoxy-D-glucose)

technique(s)

protein detection: suitable

color

, white to white with yellow cast

mp

174-176 °C

solubility

water: 49.00-51.00 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

OCC1OC(O)C(F)C(O)C1O

InChI

1S/C6H11FO5/c7-3-5(10)4(9)2(1-8)12-6(3)11/h2-6,8-11H,1H2

InChI key

ZCXUVYAZINUVJD-UHFFFAOYSA-N

Description

General description

2-Fluoro-2-deoxy-D-glucose is non-toxic and a structural analog of glucose, significantly inhibiting glycosylation. As a glucose analog, uptake of 2-Fluoro-2-deoxy-D-glucose is rapid in brain and heart cells.

2-Fluoro-2-deoxy-D-glucose can be taken up by cells but does not undergo metabolic glycolysis.

Application

2-Fluoro-2-deoxy-D-glucose is used as a tracer for rapid tumor detection. It is used as a glucose analog to study glucose uptake in mice with radiation and burn injuries. Oncology therapy studies use FDG in combination with PET (Positron Emission Topography)

Biochem/physiol Actions

Glucose analog that inhibits cellular glycosylation.

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This Item	72987	SMB00932	259580
Sigma-Aldrich F5006 2-Fluoro-2-deoxy-D-glucose	Sigma-Aldrich 72987 2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose	Sigma-Aldrich SMB00932 2-Deoxy-D-glucose 6-phosphate sodium salt	Sigma-Aldrich 259580 2-Deoxy-D-galactose
description glycosylation inhibitor, glucose analog	description ≥97% (HPLC)	description ≥98% (HPLC)	description Hexose analog that can be incorporated into rat gangliosides GM2 and GD3 in positions normally occupied by galactose.
storage temp. 2-8°C	storage temp. −20°C	storage temp. −20°C	storage temp. 10-30°C
color , white to white with yellow cast	color -	color white	color white
solubility water: 49.00-51.00 mg/mL, clear, colorless to faintly yellow	solubility -	solubility water: 50 mg/mL, clear, colorless	solubility water: 5 mg/mL
assay ≥98.00% (TLC)	assay ≥97% (HPLC)	assay ≥98% (HPLC)	assay ≥99% (HPLC)
mp 174-176 °C	mp -	mp -	mp -
concentration ≤100% (2-Fluoro-2-deoxy-D-glucose)	concentration -	concentration -	concentration -

Pictograms

GHS07

Signal Word

Warning

Hazard Codes

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves

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