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EHU157621

Sigma-Aldrich

MISSION® esiRNA

targeting human SYN2

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

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Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CCAGCATCAACTCACTGGAATCCATATACAACTTCTGTGACAAGCCATGGGTGTTTGCCCAGCTGGTCGCTATCTATAAGACACTGGGAGGAGAAAAGTTCCCTCTCATTGAACAGACATACTACCCCAACCACAAAGAGATGCTGACACTGCCCACGTTCCCTGTGGTGGTGAAGATTGGCCACGCTCACTCAGGCATGGGCAAGGTCAAAGTGGAAAACCACTACGACTTCCAGGACATTGCCAGCGTGGTGGCTCTCACCCAGACCTATGCCACTGCAGAGCCTTTCATTGACTCCAAGTATGACATCCGGGTCCAGAAGATTGGCAACAACTACAAGGCTTACATGAGGACATCGATCTCAGGGAACTGGAAGACGAACACTGGCTCTGCGATGCTGGAGCAGATTGCCATGTCAGACAGGTACAAACTGTGGGTGGACACCTGCTCTGAGATG

Ensembl | human accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Wan-You He et al.
ACS chemical neuroscience, 10(5), 2385-2396 (2019-02-21)
Painful diabetic neuropathy (PDN) is among the common complications in diabetes mellitus (DM), with its underlying mechanisms largely unknown. Synapsin II is primarily expressed in the spinal dorsal horn, and its upregulation mediates a superfluous release of glutamate and a

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