E6632
Epoxy-activated-Agarose
lyophilized powder
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About This Item
form
lyophilized powder
Quality Segment
extent of labeling
≥20 μmol per mL
technique(s)
affinity chromatography: suitable
matrix
cross-linked 4% beaded agarose
matrix active group
epoxy
matrix attachment
through epoxy to hydroxyl
matrix spacer
12 atoms
swelling
1 g swells to ~3 mL
suitability
suitable for chromatography
storage temp.
−20°C
General description
when ligands are coupled to free epoxy groups. Linkage is a stable, uncharged ether.
Epoxy-activated-Agarose is a resin. Ligands can be covalently linked to agarose via the interaction of the nucleophilic groups of the ligand with the epoxy group.
Application
Epoxy-activated-Agarose is a lyophilized powder, stabilized with lactose, which is used in affinity chromatography, protein chromatography and activated/functionalized matrices. Epoxy-activated agarose has been used in studies informing anti-proliferative activity on human-derived cancer cells as well as cancer prevention.
Physical form
Lyophilized powder stabilized with lactose
Other Notes
Ligand: 1,4-bis(2:3-Epoxypropoxy)butane
Attachment: one epoxy group
Spacer: provides a 12-atom spacer when ligands are coupled to free epoxy groups. Linkage is a stable, uncharged ether.
Attachment: one epoxy group
Spacer: provides a 12-atom spacer when ligands are coupled to free epoxy groups. Linkage is a stable, uncharged ether.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Donald Voet and Judith G. Voet
Biochemistry (2004)
Zhirong Wang et al.
Biochemical and biophysical research communications, 323(3), 743-749 (2004-09-24)
The phytochemical resveratrol (trans-3,4',5-trihydroxystilbene) is a naturally occurring polyphenol with a plethora of health-beneficial properties, including a preventive role in cancer. We surmise that resveratrol may exert its diverse biological effects by interacting with specific target proteins, denoted RTPs. To
S Ranganathan et al.
Biochimica et biophysica acta, 1182(3), 311-316 (1993-10-20)
Glyoxalase-I (Gly-I) is part of the glyoxalase system which converts methylglyoxal to D-lactic acid via an S-D-lactoylglutathione intermediate. This glutathione (GSH)-binding protein was purified from human colon tumors and corresponding normal tissue. The GSH-affinity purified fraction from normal human colon
Global Trade Item Number
| SKU | GTIN |
|---|---|
| E6632-1G | 04061826690826 |
| E6632-5G | 04061833428146 |