D2022
5,6-Dihydrothymidine
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About This Item
Empirical Formula (Hill Notation):
C10H16N2O5
CAS Number:
Molecular Weight:
244.24
UNSPSC Code:
12352204
MDL number:
storage temp.
−20°C
SMILES string
CC1CN(C2CC(O)C(CO)O2)C(=O)NC1=O
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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K A Tallman et al.
Journal of the American Chemical Society, 123(22), 5181-5187 (2001-07-18)
5,6-Dihydrothymidin-5-yl (1) was independently generated in a dinucleotide from a phenyl selenide precursor (4). Under free radical chain propagation conditions, the products resulting from hydrogen atom donation and radical-pair reaction are the major observed products in the absence of O(2).
J Cadet et al.
International journal of radiation biology and related studies in physics, chemistry, and medicine, 39(2), 119-133 (1981-02-01)
The steady-state gamma radiolysis of deaerated aqueous solutions of thymidine generated a complex mixture of pyrimidine and nucleoside derivatives. Twenty-two of these compounds have been isolated and unambiguously characterized by spectroscopic methods including proton nuclear magnetic resonance and mass spectrometry.
M Weinfeld et al.
Nucleic acids research, 21(3), 621-626 (1993-02-11)
Stacking between aromatic amino acids and nucleic acid bases may play an important role in the interaction of enzymes with nucleic acid substrates. In such circumstances, disruption of base aromaticity would be expected to decrease enzyme activity on the modified