C9650
β-Cyano-L-alanine
≥95%, suitable for ligand binding assays
Synonym(s):
3-cyano-L-alanine
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250 MG
CZK 15,400.00
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250 MG
CZK 15,400.00
About This Item
Empirical Formula (Hill Notation):
C4H6N2O2
CAS Number:
Molecular Weight:
114.10
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
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Product Name
β-Cyano-L-alanine, ≥95%
Quality Level
Assay
≥95%
form
powder
technique(s)
ligand binding assay: suitable
color
white
mp
217 °C
storage temp.
−20°C
SMILES string
OC([C@@H](N)CC#N)=O
InChI
1S/C4H6N2O2/c5-2-1-3(6)4(7)8/h3H,1,6H2,(H,7,8)/t3-/m0/s1
InChI key
BXRLWGXPSRYJDZ-VKHMYHEASA-N
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Biochem/physiol Actions
β-Cyano-L-alanine (BCA) is used as a cystathione γ-lyase (CSE) inhibitor to study the physiological roles of hydrogen sulfide in processes such as angiogenesis and hypertension.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Andrew J M Howden et al.
The Plant journal : for cell and molecular biology, 57(2), 243-253 (2008-09-13)
Pseudomonas fluorescens SBW25 is a plant growth-promoting bacterium that efficiently colonizes the leaf surfaces and rhizosphere of a range of plants. Previous studies have identified a putative plant-induced nitrilase gene (pinA) in P. fluorescens SBW25 that is expressed in the
Markus Piotrowski et al.
Plant molecular biology, 61(1-2), 111-122 (2006-06-21)
Cyanoalanine hydratase (E.C. 4.2.1.65) is an enzyme involved in the cyanide detoxification pathway of higher plants and catalyzes the hydrolysis of beta-cyano-L-alanine to asparagine. We have isolated the enzyme from seedlings of blue lupine (Lupinus angustifolius) to obtain protein sequence
Andrew G S Warrilow et al.
Journal of experimental botany, 53(368), 439-445 (2002-02-16)
The reaction mechanisms of three enzymes belonging to a single gene family are compared: a cyanoalanine synthase and two isoforms of O-acetylserine (thiol) lyase (O-ASTL) isolated from spinach (Spinacea oleracea L. cv. Medina). O-ASTL represents a major regulatory point in
B Teague et al.
British journal of pharmacology, 137(2), 139-145 (2002-09-05)
1. Sodium hydrogen sulphide (NaHS), a donor of hydrogen sulphide (H(2)S), produced dose-related relaxation of the rabbit isolated ileum (EC(50), 76.4+/-7.9 microM) and rat vas deferens (EC(50), 64.8+/-5.4 microM) and reduced ACh-mediated contraction of the guinea-pig isolated ileum. 2. NaHS
Ying-Yuan Pamela Mok et al.
British journal of pharmacology, 143(7), 881-889 (2004-10-27)
Haemorrhagic shock (60 min) in the anaesthetized rat resulted in a prolonged fall in the mean arterial blood pressure (MAP) and heart rate (HR). Pre-treatment (30 min before shock) or post-treatment (60 min after shock) with inhibitors of cystathionine gamma
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