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Merck

C6003

Chlorophyllin sodium copper salt

commercial grade, powder

Synonym(s):

Chlorophyllin, coppered trisodium salt

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5 G

CZK 1,600.00

25 G

CZK 4,260.00

100 G

CZK 12,700.00

CZK 1,600.00

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About This Item

Empirical Formula (Hill Notation):
C34H31CuN4Na3O6
CAS Number:
11006-34-1
Molecular Weight:
724.15
MDL number:
MFCD28016032
UNSPSC Code:
12171500
PubChem Substance ID:
24892826
NACRES:
NA.47
EC Number:
234-242-5

Key Documents

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Product Name

Chlorophyllin sodium copper salt,

form

powder

Quality Level

200

technique(s)

microbe id | staining: suitable

color

black, green to very dark green

solubility

H2O: 100 mg/mL, dark green

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

SMILES string

[Na+].[Na+].[Na+].CCc1c(C)c2cc3c(C=C)c(C)c4cc5nc(C(CCC([O-])=O)C5C)c(CC([O-])=O)c6c(C([O-])=O)c(C)c(cc1n2)n6[Cu]n34

InChI

1S/C34H36N4O6.Cu.3Na/c1-7-19-15(3)23-12-25-17(5)21(9-10-29(39)40)32(37-25)22(11-30(41)42)33-31(34(43)44)18(6)26(38-33)14-28-20(8-2)16(4)24(36-28)13-27(19)35-23;;;;/h7,12-14,17,21H,1,8-11H2,2-6H3,(H5,35,36,37,38,39,40,41,42,43,44);;;;/q;+2;3*+1/p-5

InChI key

HWDGVJUIHRPKFR-UHFFFAOYSA-I

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1 of 4

This Item
PHR1461B1125D8284
Chlorophyllin sodium copper salt

Sigma-Aldrich

C6003

Chlorophyllin sodium copper salt

Copper Chlorophyllin Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1461

Copper Chlorophyllin

Bathocuproinedisulfonic acid disodium salt for spectrophotometric det. of Cu, Fe

Sigma-Aldrich

B1125

Bathocuproinedisulfonic acid disodium salt

Bicinchoninic acid disodium salt hydrate ≥98% (HPLC)

Sigma-Aldrich

D8284

Bicinchoninic acid disodium salt hydrate

technique(s)

microbe id | staining: suitable

technique(s)

-

technique(s)

titration: 90% using HCLO4 (Dry Basis)

technique(s)

titration: suitable

grade

commercial grade

grade

certified reference material, pharmaceutical secondary standard

grade

-

grade

-

color

black, green to very dark green

color

-

color

white to beige

color

white to light yellow

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

pharmaceutical

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

form

powder

form

-

form

powder

form

powder

solubility

H2O: 100 mg/mL, dark green

solubility

-

solubility

H2O: 50 mg/mL

solubility

0.5% sodium bicarbonate: 50 mg/mL

Application

Chlorophyllin sodium copper salt has been used to study the effect of chlorophyllin against radiation-induced hematopoietic syndrome. It has been used to study the effect of chlorophyllin on the excretion of PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) and its metabolites into the breast-milk of lactating rats.

Biochem/physiol Actions

Chlorophyllin is a water soluble derivative of chlorophyll. It has chemopreventive properties and forms a non-covalent complex with many mutagenic/carcinogenic molecules. The complex formation reduces absorption or allows excretion of the mutagenic/carcinogenic molecules. Chlorophyllin also exhibits antioxidant, antiapoptotic and immunostimulatory effects. It provides benefits, such as prevention of body odor and increased wound healing.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SHBP2527
SHBQ0233
SHBQ0595
SHBN9046
SHBM8996

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Maria Rosaria Grossi et al.
Toxicology letters, 214(3), 235-242 (2012-09-19)
Chlorophyllin (CHL), a water soluble derivative of chlorophyll has been shown to have both anticarcinogenic and antigenotoxic properties. We evaluated the protective effects of CHL (25μM in vitro, 4 and 100mg/kg. b.w.) on the clastogenic action of two model carcinogens
Jun Zhang et al.
The Analyst, 137(18), 4287-4294 (2012-08-02)
The human hepatoma 3B cell line was chosen as an experimental model for in vitro test of drug screening. The drugs included chlorophyllin and its derivatives such as fluo-chlorophyllin, sodium copper chlorophyllin, and sodium iron chlorophyllin. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT)
Wei Li et al.
Nanomedicine (London, England), 7(3), 383-392 (2012-03-06)
How to overcome insufficient drug release is an important issue in the drug-delivery system. Here, a novel temperature and UV dual-control poly(N-isopropylacrylamide [PNIPAM]-co-chlorophyllin) nanogel was prepared via the surfactant-free emulsion polymerization. The introduction of hydrophilic chlorophyllin to the PNIPAM chain
Yan-lin Zhang et al.
Zhonghua nei ke za zhi, 51(6), 466-470 (2012-09-05)
To investigate whether chlorophyllin could protect human umbilical vein endothelial cell (HUVEC) against oxidative damage by inducing the expression of heme oxygenase-1 (HO-1) and to explore the underlying mechanism. The cellular protection of chlorophyllin against oxidative damage was detected by
Sherrill Wesley Josewin et al.
Food microbiology, 76, 219-225 (2018-09-01)
This study evaluated the potential of blue light-emitting diodes (LED) of wavelength 405 and 460 nm in combination with sodium chlorophyllin to inactivate Listeria monocytogenes and Salmonella spp. on cantaloupe rind. A cocktail culture of L. monocytogenes or Salmonella spp. strains
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Global Trade Item Number

SKUGTIN
C6003-5G04061832342085
C6003-100G04061833502969
C6003-25G04061833502976

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