C4285
Acetyl-Calpastatin (184-210) human
~95% (HPLC), powder
Synonym(s):
Acetyl-Calpain inhibitor fragment 184-210, CS peptide
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C142H230N36O44S
CAS Number:
Molecular Weight:
3177.63
UNSPSC Code:
12352200
MDL number:
Biochem/physiol Actions
Inhibitor of calpain which induces an increase in secreted amyloid β-protein 1-42.
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Robert L Campbell et al.
The Biochemical journal, 447(3), 335-351 (2012-10-06)
Calpains are a family of complex multi-domain intracellular enzymes that share a calcium-dependent cysteine protease core. These are not degradative enzymes, but instead carry out limited cleavage of target proteins in response to calcium signalling. Selective cutting of cytoskeletal proteins
Wilasinee Suwanjang et al.
Neuroscience letters, 526(1), 49-53 (2012-08-18)
Methamphetamine (METH) is an abused psychostimulant drug that can cause neurotoxicity to dopaminergic cells. It has been demonstrated that METH can induce caspase- and calpain-dependent death cascades. The purpose of the present study was to investigate the functional role of
Amy L Strong et al.
Stem cells (Dayton, Ohio), 30(12), 2774-2783 (2012-09-13)
Adipose tissue maintains a subpopulation of cells, referred to as adipose-derived stromal/stem cells (ASCs), which have been associated with increased breast cancer tumorigenesis and metastasis. For ASCs to affect breast cancer cells, it is necessary to delineate how they mobilize
Samuele De Minicis et al.
Liver international : official journal of the International Association for the Study of the Liver, 32(10), 1574-1584 (2012-09-04)
Survival of hepatic stellate cells (HSCs) is a hallmark of liver fibrosis, while the induction of HSC apoptosis may induce recovery. Activated HSC are resistant to many pro-apoptotic stimuli. To this issue, the role of Endoplasmic Reticulum (ER) stress in
R Sharma et al.
Genetika, 49(4), 505-512 (2013-07-23)
The calpains and calpastatin (CAST) make up a major cytosolic proteolytic system, the calpain-calpastatin system, found in mammalian tissues. The relative levels of the components of the calpain-calpastatin system determine the extent of meat tenderization during postmortem storage. Calpastatin (CAST)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service