C2901

Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated

Name: Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated
Brand: SIGMA
Price: 4570 CZK

≥95% (HPLC), powder

Synonym(s):

CCK-8, non-sulfated

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1 MG

CZK 4,570.00

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About This Item

Empirical Formula (Hill Notation):

C₄₉H₆₂N₁₀O₁₃S₂

CAS Number:

25679-24-7

Molecular Weight:

1063.21

NACRES:

NA.32

PubChem Substance ID:

24892546

UNSPSC Code:

12352202

MDL number:

MFCD00076488

Assay:

≥95% (HPLC)

Form:

powder

Quality level:

200

Key Documents

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InChI

1S/C49H62N10O13S2/c1-73-18-16-34(55-47(70)37(21-28-12-14-30(60)15-13-28)58-44(67)32(50)23-41(62)63)45(68)53-26-40(61)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(71)56-35(17-19-74-2)46(69)59-39(24-42(64)65)49(72)57-36(43(51)66)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52,60H,16-24,26,50H2,1-2H3,(H2,51,66)(H,53,68)(H,54,61)(H,55,70)(H,56,71)(H,57,72)(H,58,67)(H,59,69)(H,62,63)(H,64,65)

SMILES string

CSCCC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(N)CC(O)=O)C(=O)NCC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NC(CCSC)C(=O)NC(CC(O)=O)C(=O)NC(Cc4ccccc4)C(N)=O

InChI key

OIXQINQYMGNCII-UHFFFAOYSA-N

assay

≥95% (HPLC)

form

powder

UniProt accession no.

P06307

storage temp.

−20°C

Quality Level

200

Gene Information

human ... CCK(885)

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Show Differences

1 of 4

This Item	C2581	C2175	T6515
Sigma-Aldrich C2901 Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated	Sigma-Aldrich C2581 Anti-Cholecystokinin (26-33) (CCK-8) antibody produced in rabbit	Sigma-Aldrich C2175 (Tyr[SO₃H]²⁷)Cholecystokinin fragment 26-33 Amide	Sigma-Aldrich T6515 Cholecystokinin Fragment 30-33 Amide
form powder	form -	form powder	form powder
assay ≥95% (HPLC)	assay -	assay ≥97% (HPLC)	assay ≥95% (HPLC)
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
UniProt accession no. P06307	UniProt accession no. P06307	UniProt accession no. P06307, P30551, P30553	UniProt accession no. P06307, P30553
Gene Information human ... CCK(885)	Gene Information human ... CCK(885)	Gene Information human ... CCK(885) rat ... Cckar(24889), Cckbr(25706)	Gene Information human ... CCK(885) rat ... Cckbr(25706)

Application

Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated has been used in the specificity testing against gastrin and pepsinogen I proteins.

Biochem/physiol Actions

Biologically inactive form of CCK-8; CCK_B/gastrin receptor agonist that has no activity at the CCK_A receptor.

Cholecystokinin (CCK) is a 115 amino acid preprohormone and a neurotransmitter. It exists in many isoforms. The octapeptide of CCK (CCK-8S) is the most abundant form. CCK is mapped to human chromosome 3p22.1. CCK interacts with receptors of the gastrointestinal tract and nervous system. Polymorphisms in the CCK is implicated in hallucinations in patients with Parkinson′s disease. CCK plays a key role in the activation of the calcineurin-regulated nuclear factor of activated T-cells (NFATs).

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number

0000524135

0000514341

0000260807

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Advances in molecular genetics of panic disorder.

Maron E, et al.

Molecular Psychiatry, 15(7), 681-681 (2010)

Atrophic gastritis serum levels of amidated gastrin-17 and pepsinogen I in atrophic gastritis: an observational case-control study.

Sipponen P, et al.

Scandinavian Journal of Gastroenterology, 37(7), 785-791 (2002)

Cholecystokinin activates pancreatic calcineurin-NFAT signaling in vitro and in vivo.

Gurda GT, et al.

Molecular Biology of the Cell, 19(1), 198-206 (2008)

Neuropeptide regulation of fear and anxiety: Implications of cholecystokinin, endogenous opioids, and neuropeptide γ.

Bowers ME, et al.

Physiology & Behavior, 107(5), 699-710 (2012)

Genetic substrates of psychosis in patients with Parkinson's disease: a critical review.

Lenka A, et al.

Journal of the Neurological Sciences, 364(5), 33-41 (2016)

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Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated