C1011

N-Cyclohexyl-N′-(2-morpholinoethyl)carbodiimide metho-p-toluenesulfonate

≥97% (CHN)

• Synonym(s): N-Cyclohexyl-N′-(β-[N-methylmorpholino]ethyl)carbodiimide p-toluenesulfonate, CMC, CME-CDI
• Empirical Formula (Hill Notation): C₁₄H₂₆N₃O · C₇H₇O₃S
• CAS Number: 2491-17-0
• Molecular Weight: 423.57
• EC Number: 219-650-3
• UNSPSC Code: 12352200
• PubChem Substance ID: 24892296
• Beilstein/REAXYS Number: 3872192
• MDL number: MFCD00011979

Properties

• assay: ≥97% (CHN)
• form: powder
• technique(s): ligand binding assay: suitable
• color: white
• mp: 109-111 °C
• application(s): peptide synthesis
• storage temp.: −20°C
• SMILES string: Cc1ccc(cc1)S([O-])(=O)=O.C[N+]2(CCOCC2)CCN=C=NC3CCCCC3
• InChI: 1S/C14H26N3O.C7H8O3S/c1-17(9-11-18-12-10-17)8-7-15-13-16-14-5-3-2-4-6-14;1-6-2-4-7(5-3-6)11(8,9)10/h14H,2-12H2,1H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1
• InChI key: GBCAVSYHPPARHX-UHFFFAOYSA-M

Description

Application

Water-soluble condensing reagent for peptide synthesis, reagent used for coupling ligands to carriers in affinity chromatography.

Biochem/physiol Actions

N-Cyclohexyl-N′-(2-morpholinoethyl)carbodiimide (CMCT) selectively modifies/derivitizes all pseudouridine, thiouridine and 2-methylthio-6-isopentenyladenosine nucleosides for detection by methods such as matrix-assisted laser desorption/ionization mass spectrometry. CMCT, a water-soluble condensing reagent for peptide synthesis, is used as a reagent for coupling ligands to carriers in affinity chromatography.

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves