BM0028

BMS-536924

≥98% (HPLC)

• Synonym(s): 4-[[(2S)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]-3-[7-methyl-5-(4-morpholinyl)-1H-benzimidazol-2-yl]-2(1H)-pyridinone, BMS 536924
• Empirical Formula (Hill Notation): C₂₅H₂₆ClN₅O₃
• CAS Number: 468740-43-4
• Molecular Weight: 479.96
• UNSPSC Code: 12352200
• MDL number: MFCD20278190

Properties

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 10 mg/mL, clear
• storage temp.: room temp
• SMILES string: CC1=CC(N2CCOCC2)=CC3=C1NC(C4=C(NC[C@@H](O)C5=CC(Cl)=CC=C5)C=CNC4=O)=N3

Description

Biochem/physiol Actions

BMS-536924 is a potent, orally active, ATP-competitive insulin-like growth gactor-1 receptor (IGF1R) inhibitor.

BMS-536924 is a potent, orally active, ATP-competitive insulin-like growth gactor-1 receptor (IGF1R) inhibitor that shows anticancer activities in preclinical models.

Features and Benefits

BMS-536924 is available through a partnership with Bristol-Myers Squibb (BMS). To learn more and view other BMS compounds, visit sigma.com/BMS.

Legal Information

Sold for research purposes only under agreement from BMS.

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable