B3188

BYK204165

≥98% (HPLC)

• Synonym(s): 4-(1-methyl-1H-pyrrol-2-ylmethylene)-4H-isoquinolin-1,3-dione
• Empirical Formula (Hill Notation): C₁₅H₁₂N₂O₂
• CAS Number: 1104546-89-5
• Molecular Weight: 252.27
• NACRES: NA.77
• PubChem Substance ID: 329773214
• UNSPSC Code: 12352200
• MDL number: MFCD12912397
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: yellow
• solubility: DMSO: >20 mg/mL
• storage temp.: 2-8°C
• SMILES string: Cn1cccc1\C=C2/C(=O)NC(=O)c3ccccc23
• InChI: 1S/C15H12N2O2/c1-17-8-4-5-10(17)9-13-11-6-2-3-7-12(11)14(18)16-15(13)19/h2-9H,1H3,(H,16,18,19)/b13-9-
• InChI key: BTYSIDSTHDDAJW-LCYFTJDESA-N
• Gene Information: human ... PARP1(142) ; mouse ... PARP1(11545) ; rat ... PARP1(25591)

Description

Biochem/physiol Actions

BYK204165 is a potent and selective inhibitor of poly(ADP-ribose) polymerase 1 (PARP1). It is 100-fold selective for PARP-1 over PARP-2.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H317
• pcodes: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable