B013
N-(2-Chloroethyl)-N-ethyl-2-methylbenzylamine hydrochloride
solid
Synonym(s):
2-CEA, N-Ethyl-N-(2-chloroethyl)-2-methylbenzylamine hydrochloride, Xylamine hydrochloride
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C12H18ClN · HCl
CAS Number:
Molecular Weight:
248.19
MDL number:
UNSPSC Code:
12352103
form
solid
color
white
solubility
H2O: soluble
ethanol: soluble
methanol: soluble
SMILES string
Cl.CCN(CCCl)Cc1ccccc1C
Looking for similar products? Visit Product Comparison Guide
Biochem/physiol Actions
Selective, irreversible blocker of norepinephrine transport into central and peripheral neurons.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Y Huang
European journal of pharmacology, 327(1), 41-47 (1997-05-26)
The effects of noradrenaline uptake inhibitors on contractions evoked by electric field stimulation, noradrenaline, clonidine. 5-hydroxytryptamine, ATP, high K+, and BaCl2 in the epididymal half of rat isolated vas deferens were examined. Protriptyline, amitriptyline and xylamine concentration-dependently inhibited monophasic contractions
R W Ransom et al.
Life sciences, 37(13), 1177-1182 (1985-09-30)
Xylamine (XYL) administered to intact rats caused a 70-80% reduction in norepinephrine (NE) uptake by the vas deferens but had little or no effect on NE content in that tissue. The vas deferens accumulates 3H-XYL in vitro by a desmethylimipramine
J B Fischer et al.
The Journal of pharmacology and experimental therapeutics, 226(3), 650-655 (1983-09-01)
The accumulation of tritium-labeled xylamine ([3H]XYL), an irreversible inhibitor of neuronal norepinephrine (NE) uptake, was studied in organ-cultured rat superior cervical ganglia (SCG). At concentrations below those which significantly inhibit NE uptake, [3H]XYL accumulation was linear with time for up
T K Chang et al.
Brain research, 597(1), 162-165 (1992-11-27)
Primary astrocyte cultures from neonatal rat brains show a Na+-dependent, desipramine-sensitive uptake of [3H]norepinephrine ([3H]NE). Xylamine, a nitrogen mustard, attenuated this uptake of [3H]NE into the astrocytes (IC50 = 0.8 microM). The dose-dependent reduction of [3H]NE uptake by xylamine indicated
B A Faraj et al.
Pharmacology, 48(5), 320-327 (1994-05-01)
The main objective of the present investigation was to determine whether the uptake of [3H]-dopamine in human lymphocytes is mediated through a serotonin transporter. This was examined by studying the effects of various monoamine uptake inhibitors on the uptake of
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service