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Key Documents

AV35750

Sigma-Aldrich

Anti-ONECUT2 antibody produced in rabbit

IgG fraction of antiserum

Synonym(s):

Anti-One cut domain, family member 2

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100 μL
CZK 9,920.00

CZK 9,920.00

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100 μL
CZK 9,920.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

CZK 9,920.00

Please contact Customer Service for Availability

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

52 kDa

species reactivity

human, rabbit, mouse, rat, horse, guinea pig, bovine, dog

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_004843

UniProt accession no.

O95948

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ONECUT2(9480)

Immunogen

Synthetic peptide directed towards the middle region of human ONECUT2

Biochem/physiol Actions

ONECUT2 belongs to onecut family of transcription factors that regulate melanocyte and hepatocyte differentiation.

Sequence

Synthetic peptide located within the following region: NGLHHPGHTQSHGPVLAPSRERPPSSSSGSQVATSGQLEEINTKEVAQRI

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
QC5087

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Frédéric Clotman et al.
Genes & development, 19(16), 1849-1854 (2005-08-17)
During liver development, hepatocytes and biliary cells differentiate from common progenitors called hepatoblasts. The factors that control hepatoblast fate decision are unknown. Here we report that a gradient of activin/TGFbeta signaling controls hepatoblast differentiation. High activin/TGFbeta signaling is required near

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