This product is a research grade chemical and not a pharmaceutical product. While the same active enantiomer (R-(−)-apomorphine) is an approved medicine, it is not manufactured, packaged, or regulated as a clinical dosage form, so it should not be used in humans.
A4393
R-(−)-Apomorphine hydrochloride hemihydrate
calcined, ≥98% (with NaOH, titration)
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| Size/SKU | Availability | Price |
|---|---|---|
100 mg | Please contact Customer Service for Availability | 1 440,00 CZK |
250 mg | Please contact Customer Service for Availability | 2 370,00 CZK |
1 g | Please contact Customer Service for Availability | 7 250,00 CZK |
5 g | Please contact Customer Service for Availability | 29 100,00 CZK |
About This Item
Linear Formula:
C17H17NO2 · HCl · 1/2H2O
CAS Number:
Molecular Weight:
312.79
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352210
EC Number:
206-243-0
MDL number:
Assay:
≥98% (with NaOH, titration)
Form:
calcined, (Powder to Crystalline Powder)
Storage condition:
protect from light, under inert gas
Quality Segment
assay
≥98% (with NaOH, titration)
form
calcined, (Powder to Crystalline Powder)
storage condition
protect from light, under inert gas
color
white to gray
mp
285-287 °C (lit.)
solubility
H2O: ~10 mg/mL, clear, yellow-green
SMILES string
Cl[H].Cl[H].[H]O[H].[H][C@]12Cc3ccc(O)c(O)c3-c4cccc(CCN1C)c24.[H][C@]56Cc7ccc(O)c(O)c7-c8cccc(CCN5C)c68
InChI
1S/2C17H17NO2.2ClH.H2O/c2*1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12;;;/h2*2-6,13,19-20H,7-9H2,1H3;2*1H;1H2/t2*13-;;;/m11.../s1
InChI key
CXWQXGNFZLHLHQ-DPFCLETOSA-N
Gene Information
human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816)
Application
Biochem/physiol Actions
R-(−)-Apomorphine acts as a non-selective D1 and D2 dopamine receptor agonist. It shows therapeutic effects against Parkinson′s disease and male erectile dysfunction. R-(−)-Apomorphine also shows neuroprotective, radical scavenging, and emetic effects. Apomorphine stimulates the brain chemoreceptor trigger zone. It stimulates the chemoreceptor trigger zone in the brain.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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