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Merck

A024

MECA

solid

Synonym(s):

5′-N-Methylcarboxamidoadenosine

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About This Item

Empirical Formula (Hill Notation):
C11H14N6O4
CAS Number:
35788-27-3
Molecular Weight:
294.27
UNSPSC Code:
12352200
MDL number:
MFCD00069197

Key Documents

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Product Name

MECA, solid

SMILES string

CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)ncnc23

form

solid

color

white

solubility

0.1 M HCl: soluble
H2O: slightly soluble
ethanol: slightly soluble

Gene Information

human ... ADORA2A(135), ADORA2B(136)

Biochem/physiol Actions

A2 adenosine receptor agonist.

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Certificates of Analysis (COA)

Lot/Batch Number
113K4703
111K47101
113K47031
111K4710

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R F Bruns et al.
Molecular pharmacology, 29(4), 331-346 (1986-04-01)
[3H]NECA (1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-beta-D-ribofuronamide) is known to bind to both the A1 and A2 subtypes of adenosine receptor in rat striatal membranes. In order to study the putative A2 component of [3H]NECA binding, we examined several compounds for the ability to selectively

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