This product is not tested for RNase activity. Currently, an RNAse tested PMSF product is not available.
93482
Phenylmethanesulfonyl fluoride solution
~0.1 M in ethanol (T)
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Synonym(s):
Benzylsulfonyl fluoride, PMSF
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| Size/SKU | Availability | Price |
|---|---|---|
50 mL | Please contact Customer Service for Availability | 2 840,00 CZK |
250 mL | Please contact Customer Service for Availability | 11 200,00 CZK |
About This Item
CAS Number:
UNSPSC Code:
12352202
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2088311
2 840,00 CZK
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Please contact Customer Service for Availability
Quality Segment
biological source
microbial, synthetic
form
liquid
concentration
~0.1 M in ethanol (T)
input
general use sample(s)
density
0.797 g/mL at 20 °C
storage temp.
2-8°C
SMILES string
FS(=O)(=O)Cc1ccccc1
InChI
1S/C7H7FO2S/c8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2
InChI key
YBYRMVIVWMBXKQ-UHFFFAOYSA-N
Application
Phenylmethanesulfonyl fluoride solution has been used as a component in the cell lysate buffer in breast adenocarcinoma cell line, fibrosarcoma cell line and D5 hindbrain and spinal cord neural progenitors.
Biochem/physiol Actions
Administration of PMSF produces analgesia unrelated to its anticholinesterase effect, and prolongs the analagesic effect of centrally administered β-endorphin.
Phenylmethanesulfonyl fluoride (PMSF) is a serine protease inhibitor. It binds covalently to active site residue of proteases and prevents proteolytic activity. PMSF is used in cell lysate buffers during protein purification to prevent target protein degradation. PMSF effectively inhibits the naloxone-precipitated withdrawal jumping.
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This Item | |||
|---|---|---|---|
| description ~0.1 M in ethanol (T) | description ≥99.0% (T) | description Phenylmethylsulfonyl Fluoride, CAS 329-98-6, is an irreversible inhibitor of serine proteases. It causes sulfonylation of the active-site serine residues. | description granular, 98% |
| biological source synthetic, microbial | biological source synthetic | biological source - | biological source - |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| form liquid | form powder or crystals | form crystalline solid | form granular |
| storage temp. 2-8°C | storage temp. room temp | storage temp. 10-30°C | storage temp. - |
| density 0.797 g/mL at 20 °C | density - | density - | density - |
| input general use sample(s) | input general use sample(s) | input - | input - |
Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2
Storage Class
3 - Flammable liquids
WGK
WGK 2
Flash Point (°F)
53.6 °F - closed cup
Flash Point (°C)
12 °C - closed cup
PPE (personal protective equipment)
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Regulatory Listings
Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.
64-17-5
CAS No.
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Is this product 93482 RNase-free?
1 answer-
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How can I further dilute Product 93482, Phenylmethanesulfonyl fluoride solution?
1 answer-
We would recommend that you use an anhydrous ethanol to further dilute this solution, since PMSF is very unstable in water.
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What can Product 93482, Phenylmethanesulfonyl fluoride solution, be used for?
1 answer-
PMSF is a serine protease inhibitor, inhibiting the activity of enzymes such as thrombin, trypsin, papain, chymotrypsin and proteinase K. It also inhibits mammalian acetylcholinesterases.
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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