91211

Oxyresveratrol

≥97.0% (HPLC)

• Synonym(s): (E)-2,3′,4,5′-Stilbenetetrol, 2,3′,4,5′-Tetrahydroxy-trans-stilbene, 4-[(1E)-2-(3,5-Dihydroxyphenyl)ethenyl]-1,3-benzenediol
• Empirical Formula (Hill Notation): C₁₄H₁₂O₄
• CAS Number: 29700-22-9
• Molecular Weight: 244.24
• NACRES: NA.25
• PubChem Substance ID: 329770004
• UNSPSC Code: 12352200
• MDL number: MFCD11974969

Properties

• Quality Segment: 100
• assay: ≥97.0% (HPLC)
• form: solid
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• SMILES string: Oc1ccc(\C=C\c2cc(O)cc(O)c2)c(O)c1
• InChI: 1S/C14H12O4/c15-11-4-3-10(14(18)8-11)2-1-9-5-12(16)7-13(17)6-9/h1-8,15-18H/b2-1+
• InChI key: PDHAOJSHSJQANO-OWOJBTEDSA-N

Description

General description

Oxyresveratrol (OXY or ORV) is a naturally occurring polyphenolic stilbene that is predominantly present in the heartwood of many plants.[1][2] It is primarily extracted from Artocarpus lakoocha Roxb. plant[3][4], and is one of the main constituents of this plant.[1] ORV has a very simple chemical structure with a trans-1,2-diphenylethylene in its core and two hydroxyls (OH) groups attached to each aromatic ring.[2]

Application

Oxyresveratrol has been used:

• with poly(lactic-co-glycolic acid) (PLGA) nanoparticles to test its antioxidant effects and to investigate its role in the inhibition of superoxide anion (O₂^-) generation[3]
• to test its effects as an anti-neuroinflammatory agent on interleukin-1 beta (IL-1β)-induced HMC3 human microglial cell line[4]
• as a reference standard to determine its existence in Artocarpus lakoocha Roxb. (AL) extract using high-performance liquid chromatography (HPLC)[1]

Biochem/physiol Actions

Oxyresveratrol is well-known due to its diverse biological and pharmacological properties.[2] It is a potent antioxidant and anti-inflammatory agent.[2] ORV also exerts neuroprotective activities and protects against cerebral ischemia, stroke, and several neurodegenerative disorders.[2] It also displays anti-cancer, antimicrobial, hepatoprotective properties and protects against several other metabolic disorders.[2] It is also a potent tyrosinase inhibitor.[2]

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H315,H318,H335
• pcodes: P280 - P302 + P352 - P305 + P351 + P338 + P310
• Hazard Classifications: Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable