6902-50A

Human Peripheral Blood T Cells: HPBT

• NACRES: NA.81
• UNSPSC Code: 41106514
• Biological source: human peripheral blood
• Growth mode: Suspension

Properties

• biological source: human peripheral blood
• form: liquid
• packaging: pkg of 5,000,000 cells
• manufacturer/tradename: Cell Applications, Inc
• growth mode: Suspension
• technique(s): cell culture | mammalian: suitable
• shipped in: dry ice
• storage temp.: −196°C

Description

General description

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Human Peripheral Blood T Cells (HPBT) provide a useful in vitro tool for studying the biology and pathology of CD4⁺ cells. HPBT cells play critical roles in the regulation of immune responses, and are responsible for mediating many of the effector mechanisms of the immune system. Increased activity in the field of immunotherapy, coupled with the expense of clinical trials, has led to renewed interest in obtaining high purity human T cells to meet needs for research and development. Our CD4⁺ T Cells are isolated from human blood of healthy donors and cryopreserved immediately after isolation.

Application

Pathology, cancer, autoimmune disorders, infectious diseases. Immune response regulation, direct destruction of infected cells, immunocompetence, scanning of intracellular environment, effector mechanisms, realistic in vitro model, immunotherapeutics. T cell origination, development, differentiation, expansion, proliferation, maturation and activation. Hematopoesis, stem cells, positive & negative selection. T cell receptors (TCRs), antigen recognition, costimulatory molecules, interaction with foreign antigens, signaling cascades and cytokine production.

Biochem/physiol Actions

Blood

Packaging

Immediately after isolation, 5,000,000 cells in DMEM containing 45% FBS & 10% DMSO.

Analysis Note

Each lot was tested for proper morphology, CD4 positive selection, Negative for HIV, Hepatitis B, Hepatitis C

Other Notes

DMEM containing 45% FBS & 10% DMSO

Disclaimer

This product is regulated in France when intended for scientific purposes, including import, export, and conservation activities (Articles L.1211-1, paragraph 2, and L.1243-4 of the French Public Health Code). The purchaser (i.e. end user) is required to obtain an import authorization from the France Ministry responsible for Research (as referenced in Article L.1245-5-1 II of the French Public Health Code) or a conservation authorization from the same ministry (as referenced in Article L.1243-4 of the French Public Health Code). By placing an order for this product, you confirm that you have obtained the appropriate import or conservation authorization for the product. For more information regarding the use of human biological samples for research purposes in France, please contact the relevant French authorities.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable