44796
Texas Red®-2-sulfonamidoethyl methanethiosulfonate
suitable for fluorescence
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About This Item
Empirical Formula (Hill Notation):
C34H37N3O8S4
CAS Number:
Molecular Weight:
743.93
PubChem Substance ID:
UNSPSC Code:
12352200
fluorescence
λex 588 nm; λem 609 nm in 0.1 M phosphate pH 7.0
suitability
suitable for fluorescence
storage temp.
−20°C
SMILES string
CS(=O)(=O)SCCNS(=O)(=O)c1ccc(c(c1)S([O-])(=O)=O)C2=C3C=C4CCC[N+]5=C4C(CCC5)=C3Oc6c7CCCN8CCCc(cc26)c78
InChI
1S/C34H37N3O8S4/c1-47(38,39)46-17-12-35-48(40,41)23-10-11-24(29(20-23)49(42,43)44)30-27-18-21-6-2-13-36-15-4-8-25(31(21)36)33(27)45-34-26-9-5-16-37-14-3-7-22(32(26)37)19-28(30)34/h10-11,18-20,35H,2-9,12-17H2,1H3
InChI key
DHYGLLUUGIYOPV-UHFFFAOYSA-N
Application
Texas Red-2-sulfonamidoethyl methanethiosulfonate (Texas Red-2-MTS), S-alkylating, may be use to label S-nitrosothiol and sulfhydryl (cysteine) containing compounds such as proteins for detection with fluorescence applications.
Analysis Note
degree of coupling ≥20%
Legal Information
Texas Red is a registered trademark of Life Technologies
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Yi Yang et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(1), 117-122 (2004-12-25)
Protein S-nitrosation represents a recently described form of post-translational modification that is rapid and reversible. However, the analysis of protein S-nitrosation in situ has been difficult because of the absence of specific probes and the instability of cellular protein S-nitrosothiols.
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