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1,8-Dihydroxy-3-methylanthraquinone

Name: 1,8-Dihydroxy-3-methylanthraquinone
Brand: SIGMA
Price: 2880 CZK

98%

Synonym(s):

3-Methylchrysazin, Chrysophanic acid

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Size/SKU	Availability	Price
50 mg	Please contact Customer Service for Availability	2 880,00 CZK
1 g	Please contact Customer Service for Availability	23 300,00 CZK

About This Item

Empirical Formula (Hill Notation):

C₁₅H₁₀O₄

CAS Number:

481-74-3

Molecular Weight:

254.24

UNSPSC Code:

51102829

NACRES:

NA.85

PubChem Substance ID:

57648009

EC Number:

207-572-2

Beilstein/REAXYS Number:

1252300

MDL number:

MFCD00001208

2 880,00 CZK

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Properties

Quality Segment

100

assay

98%

form

crystalline

color

yellow-orange

solubility

chloroform: 1%

antibiotic activity spectrum

neoplastics, viruses

mode of action

enzyme | inhibits

SMILES string

Cc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1

InChI

1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3

InChI key

LQGUBLBATBMXHT-UHFFFAOYSA-N

Gene Information

human ... ELA2(1991)

Description

Application

Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells . It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro .

Biochem/physiol Actions

Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway . Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus .

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

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This Item	O5636	C2632	PHL89378
Sigma-Aldrich 229075 1,8-Dihydroxy-3-methylanthraquinone	Sigma-Aldrich O5636 9,12-Octadecadiynoic acid	Sigma-Aldrich C2632 CAPS	PHL89378 Chrysophanol
description 98%	description ≥98%	description ≥99%	description phyproof^® Reference Substance
antibiotic activity spectrum neoplastics, viruses	antibiotic activity spectrum -	antibiotic activity spectrum -	antibiotic activity spectrum -
mode of action enzyme \| inhibits	mode of action -	mode of action -	mode of action -
Quality Level 100	Quality Level 200	Quality Level 400	Quality Level -
assay 98%	assay ≥98%	assay ≥99%	assay ≥95.0% (HPLC)
form crystalline	form crystalline	form crystalline powder	form crystals
solubility chloroform: 1%	solubility water: slightly soluble	solubility H₂O: soluble 15g + 85 mL, clear, colorless	solubility -

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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