21953

5(6)-Carboxytetramethylrhodamine

BioReagent, suitable for fluorescence, ≥85% (sum of isomers, HPCE)

• Empirical Formula (Hill Notation): C₂₅H₂₂N₂O₅
• CAS Number: 98181-63-6
• Molecular Weight: 430.45
• NACRES: NA.32
• PubChem Substance ID: 329752227
• UNSPSC Code: 12352116
• MDL number: MFCD16661194

Properties

• product line: BioReagent
• Quality Segment: 100
• assay: ≥85% (sum of isomers, HPCE)
• form: solid
• mp: ≥300 °C (lit.)
• solubility: DMF: soluble, DMSO: soluble
• fluorescence: λ_ex 543 nm; λ_em 572 nm in methanol
• suitability: suitable for fluorescence
• SMILES string: CN(C)c1ccc2c(Oc3cc(ccc3C24OC(=O)c5cc(ccc45)C(O)=O)N(C)C)c1.CN(C)c6ccc7c(Oc8cc(ccc8C79OC(=O)c%10ccc(cc9%10)C(O)=O)N(C)C)c6
• InChI: 1S/2C25H22N2O5/c1-26(2)15-6-9-19-21(12-15)31-22-13-16(27(3)4)7-10-20(22)25(19)18-8-5-14(23(28)29)11-17(18)24(30)32-25;1-26(2)15-6-9-18-21(12-15)31-22-13-16(27(3)4)7-10-19(22)25(18)20-11-14(23(28)29)5-8-17(20)24(30)32-25/h2*5-13H,1-4H3,(H,28,29)
• InChI key: LBUFYZITRTUEFI-UHFFFAOYSA-N

Description

Application

5(6)-Carboxytetramethylrhodamine (TAMRA, TMR) may be used as a fluorescence probe to study the distribution of molecules such as cell-penetrating peptides (CPPs) and as fluorescence partner in applications such as two-dimensional fluorescence intensity distribution analysis (2D-FIDA), luminescence resonance energy transfer (LRET) and fluorescence resonance energy transfer (FRET).

Reacts with primary and secondary amine groups on proteins, nucleic acids and other biomolecules.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)