Z2376

Zinquin

≥95% (HPLC), solid

• Synonym(s): 2-[[2-Methyl-8-[[(4-methylphenyl)sulfonyl]amino]-6-quinolinyl]oxy]acetic acid, Zinquin A
• Empirical Formula (Hill Notation): C₁₉H₁₈N₂O₅S
• CAS Number: 151606-29-0
• Molecular Weight: 386.42
• NACRES: NA.21
• PubChem Substance ID: 329831606
• UNSPSC Code: 12352100
• MDL number: MFCD03452711

Properties

• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: solid
• color: off-white
• solubility: DMSO: soluble, methanol: soluble
• functional group: carboxylic acid
• storage temp.: 2-8°C
• SMILES string: Cc1ccc(cc1)S(=O)(=O)Nc2cc(OCC(O)=O)cc3ccc(C)nc23
• InChI: 1S/C19H18N2O5S/c1-12-3-7-16(8-4-12)27(24,25)21-17-10-15(26-11-18(22)23)9-14-6-5-13(2)20-19(14)17/h3-10,21H,11H2,1-2H3,(H,22,23)
• InChI key: CGNKOBNGEFZRQU-UHFFFAOYSA-N

Description

Application

Zinquin has been used to detect intracellular zinc.

Biochem/physiol Actions

Zinquin is a membrane-permeant fluorophore. It is used to detect zinc in cells by UV fluorescence. Zinquin ethyl ester can be used to monitor the change in intracellular concentrations of Zn²⁺ in thymocytes and hepatocytes. The ester is excited at 368nm and emits at 490nm.

Other Notes

Free acid or salt as available

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)