N0750010

Nifedipine impurity A

European Pharmacopoeia (EP) Reference Standard

• Synonym(s): Oxidized Nifedipine, 2,6-Dimethyl-4-(2´-nitrophenyl)-3,5-pyridinecarboxylic acid dimethyl ester
• Empirical Formula (Hill Notation): C₁₇H₁₆N₂O₆
• CAS Number: 67035-22-7
• Molecular Weight: 344.32
• NACRES: NA.24
• PubChem Substance ID: 329818456
• UNSPSC Code: 41116107
• MDL number: MFCD00153847

Properties

• grade: pharmaceutical primary standard
• API family: nifedipine
• manufacturer/tradename: EDQM
• application(s): pharmaceutical (small molecule); pharmaceutical
• format: neat
• SMILES string: COC(=O)c1c(C)nc(C)c(C(=O)OC)c1-c2ccccc2[N+]([O-])=O
• InChI: 1S/C17H16N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8H,1-4H3
• InChI key: UMQHJQGNGLQJPF-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Nifedipine impurity A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

CYP3A4 nifedipine metabolite. Nifedipine (parent compound) is an antianginal and antihypertensive agent.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Codes: H318
• Precautionary Statements: P280 - P305 + P351 + P338 + P310
• Hazard Classifications: Eye Dam. 1
• Storage Class: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable