BP650

Terfenadine

British Pharmacopoeia (BP) Reference Standard

• Synonym(s): α-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol
• Empirical Formula (Hill Notation): C₃₂H₄₁NO₂
• CAS Number: 50679-08-8
• Molecular Weight: 471.67
• UNSPSC Code: 41116107
• NACRES: NA.24
• MDL number: MFCD00079622

Properties

• grade: pharmaceutical primary standard
• API family: terfenadine
• form: crystalline powder
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: BP
• application(s): pharmaceutical; pharmaceutical small molecule
• format: neat
• storage temp.: 2-8°C
• SMILES string: CC(C)(C)c1ccc(cc1)C(O)CCCN2CCC(CC2)C(O)(c3ccccc3)c4ccccc4
• InChI: 1S/C32H41NO2/c1-31(2,3)26-18-16-25(17-19-26)30(34)15-10-22-33-23-20-29(21-24-33)32(35,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-14,16-19,29-30,34-35H,10,15,20-24H2,1-3H3
• InChI key: GUGOEEXESWIERI-UHFFFAOYSA-N
• Gene Information: human ... HRH1(3269)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Terfenadine BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Biochem/physiol Actions

Non-sedating second generation H1 histamine receptor antagonist.

Non-sedating second generation H1 histamine receptor antagonist. Mainly metabolized by Cyp3A4, 5, 7. Inhibits CYP2C8.

Packaging

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Other Notes

Sales restrictions may apply.

Safety Information

• hcodes: H413
• pcodes: P273 - P501
• Hazard Classifications: Aquatic Chronic 4
• Storage Class: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable