BP199

Hyoscine hydrobromide

British Pharmacopoeia (BP) Reference Standard

• Synonym(s): (−)-Scopolamine hydrobromide trihydrate, Hyoscine hydrobromide, Scopine tropate
• Empirical Formula (Hill Notation): C₁₇H₂₁NO₄ · HBr · 3H₂O
• CAS Number: 6533-68-2
• Molecular Weight: 438.31
• EC Number: 204-050-6
• UNSPSC Code: 41116107
• NACRES: NA.24
• Beilstein/REAXYS Number: 6100669
• MDL number: MFCD00150066

Properties

• grade: pharmaceutical primary standard
• API family: hyoscine, scopolamine
• form: powder
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: BP
• mp: 195-199 °C (dry matter) (lit.)
• application(s): pharmaceutical; pharmaceutical small molecule
• format: neat
• storage temp.: 2-8°C
• SMILES string: O.O.O.Br.CN1[C@@H]2C[C@H](C[C@H]1[C@@H]3O[C@H]23)OC(=O)[C@H](CO)c4ccccc4
• InChI: 1S/C17H21NO4.BrH.3H2O/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;;;;/h2-6,11-16,19H,7-9H2,1H3;1H;3*1H2/t11-,12-,13-,14+,15-,16+;;;;/m1..../s1
• InChI key: LACQPOBCQQPVIT-SEYKEWMNSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Hyoscine hydrobromide BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Biochem/physiol Actions

Competitive nonselective muscarinic acetylcholine antagonist.

Competitive nonselective muscarinic acetylcholine antagonist. Scopolamine-induced amnesia in laboratory animals is a commonly-used model of memory deficit.

Packaging

Unit quantity: 200 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H300 + H310 + H330
• pcodes: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable