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WB-4101 hydrochloride

Name: WB-4101 hydrochloride
Brand: SIAL
Price: 3330 CZK

analytical standard

Synonym(s):

2-[(2,6-Dimethoxyphenoxyethyl)aminomethyl]-1,4-benzodioxane hydrochloride

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Pack Size	SKU	Availability	Price
100 mg		Please contact Customer Service for Availability	CZK 3,330.00

About This Item

Empirical Formula (Hill Notation):

C₁₉H₂₃NO₅ · HCl

CAS Number:

2170-58-3

Molecular Weight:

381.85

NACRES:

NA.24

PubChem Substance ID:

329773098

UNSPSC Code:

41116107

EC Number:

218-520-3

MDL number:

MFCD00055187

CZK 3,330.00

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Properties

grade

analytical standard

Quality Level

100

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

format

neat

SMILES string

Cl.COc1cccc(OC)c1OCCNCC2COc3ccccc3O2

InChI

1S/C19H23NO5.ClH/c1-21-17-8-5-9-18(22-2)19(17)23-11-10-20-12-14-13-24-15-6-3-4-7-16(15)25-14;/h3-9,14,20H,10-13H2,1-2H3;1H

InChI key

KAHMEWANVDFFCQ-UHFFFAOYSA-N

Description

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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This Item	68631	53183	75024
Supelco B018 WB-4101 hydrochloride	Supelco 68631 (±)-Octopamine hydrochloride	Supelco 53183 Metformin-(dimethyl-d₆) hydrochloride	Supelco 75024 3-Methoxytyramine hydrochloride
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
grade analytical standard	grade analytical standard	grade analytical standard	grade analytical standard
format neat	format neat	format neat	format neat

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

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alpha-Adrenoceptor-mediated depletion of phosphatidylinositol 4, 5-bisphosphate inhibits activation of volume-regulated anion channels in mouse ventricular myocytes.

K Ichishima et al.

British journal of pharmacology, 161(1), 193-206 (2010-08-20)

Volume-regulated anion channels (VRACs) play an important role in cell-volume regulation. alpha(1)-Adrenoceptor stimulation by phenylephrine (PE) suppressed the hypotonic activation of VRAC current in mouse ventricular cells and regulatory volume decrease (RVD) was also absent in PE-treated cells. We examined

Affinity and activity profiling of unichiral 8-substituted 1,4-benzodioxane analogues of WB4101 reveals a potent and selective α1B-adrenoceptor antagonist.

Laura Fumagalli et al.

European journal of medicinal chemistry, 58, 184-191 (2012-11-06)

Unichiral 8-substituted analogues of 2-[(2-(2,6-dimethoxyphenoxy)ethyl)aminomethyl]-1,4-benzodioxane (WB4101) were synthesized and tested for binding affinity at cloned human α(1a)-, α(1b)-and α(1d)-adrenoreceptor (α(1a)-, α(1b)-and α(1d)-AR) and at native rat 5-HT(1A) receptor and for antagonist affinity at α(1A)-, α(1B)-and α(1D)-AR and at α(2A/D)-AR. Among

Analgesia induced by 2- or 100-Hz electroacupuncture in the rat tail-flick test depends on the activation of different descending pain inhibitory mechanisms.

Josie R T Silva et al.

The journal of pain : official journal of the American Pain Society, 12(1), 51-60 (2010-06-18)

We evaluated the effectiveness of intrathecal antagonists of α1- (WB4101) and α2- (idazoxan) adrenoceptors and serotonergic (methysergide), opioid (naloxone), muscarinic (atropine), GABA(A) (bicuculline) and GABA(B) (phaclofen) receptors in blocking 2- or 100-Hz electroacupuncture (EA)-induced analgesia (EAIA) in the rat tail-flick

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Global Trade Item Number

SKU	GTIN
B018-100MG	04061832847658

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WB-4101 hydrochloride

analytical standard

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About This Item

CZK 3,330.00

grade

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technique(s)

format

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InChI

InChI key

Application

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This Item

Safety Information

Storage Class

wgk

flash_point_f

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ppe

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Skip To

WB-4101 hydrochloride

analytical standard

Select a Size

About This Item

B018-100MG

CZK 3,330.00

grade

Quality Level

technique(s)

format

SMILES string

InChI

InChI key

Application

Compare Similar Items

This Item

Safety Information

Storage Class

wgk

flash_point_f

flash_point_c

ppe

Documentation

Certificates of Analysis (COA)

Already Own This Product?

Peer Reviewed Papers

Global Trade Item Number

Questions

Reviews

Active Filters