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A1330000

Aspartic acid

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

L-Aspartic acid, (S)-(+)-Aminosuccinic acid, (S)-Aminobutanedioic acid

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About This Item

Linear Formula:
HO2CCH2CH(NH2)CO2H
CAS Number:
56-84-8
Molecular Weight:
133.10
Beilstein:
1723530
MDL number:
MFCD00002616
UNSPSC Code:
41116107
PubChem Substance ID:
329770359
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

aspartic acid

manufacturer/tradename

EDQM

mp

>300 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

N[C@@H](CC(O)=O)C(O)=O

InChI

1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1

InChI key

CKLJMWTZIZZHCS-REOHCLBHSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Aspartic acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Principal neurotransmitter for fast synaptic excitation.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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R A Azevedo et al.
Amino acids, 30(2), 143-162 (2006-03-10)
Aspartate is the common precursor of the essential amino acids lysine, threonine, methionine and isoleucine in higher plants. In addition, aspartate may also be converted to asparagine, in a potentially competing reaction. The latest information on the properties of the
E R Waite et al.
Forensic science international, 103(2), 113-124 (1999-09-11)
Accurate age determination of adult cadavers and human remains is a key requirement in forensic practice. The current morphological methods lack accuracy and precision, require specialist training and are costly. The use of aspartic acid racemization (AAR) in human dentine
Stefanie Ritz-Timme et al.
Ageing research reviews, 1(1), 43-59 (2002-06-01)
Aspartic acid racemization (AAR) represents one of the major types of non-enzymatic covalent modification that leads to an age-dependent accumulation of abnormal protein in numerous human tissues. In vivo racemization is an autonomic process during the "natural" ageing of proteins
M J Collins et al.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 354(1379), 51-64 (1999-03-26)
The increase in proportion of the non-biological (D-) isomer of aspartic acid (Asp) relative to the L-isomer has been widely used in archaeology and geochemistry as a tool for dating. the method has proved controversial, particularly when used for bones.
Víctor A Lórenz-Fonfría et al.
Biochimica et biophysica acta, 1837(5), 626-642 (2013-11-12)
The new and vibrant field of optogenetics was founded by the seminal discovery of channelrhodopsin, the first light-gated cation channel. Despite the numerous applications that have revolutionised neurophysiology, the functional mechanism is far from understood on the molecular level. An
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