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Fusarenon X

analytical standard

Synonym(s):

3α,7α,15-Trihydroxy-4β-acetoxy-12,13-epoxytrichothec-9-en-8-one

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About This Item

Empirical Formula (Hill Notation):
C17H22O8
CAS Number:
Molecular Weight:
354.35
UNSPSC Code:
85151701
NACRES:
NA.24

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

−20°C

SMILES string

CC(=O)O[C@@H]1[C@@H](O)[C@H]2O[C@@H]3C=C(C)C(=O)[C@@H](O)[C@]3(CO)[C@]1(C)[C@]24CO4

InChI

1S/C17H22O8/c1-7-4-9-16(5-18,12(22)10(7)20)15(3)13(24-8(2)19)11(21)14(25-9)17(15)6-23-17/h4,9,11-14,18,21-22H,5-6H2,1-3H3/t9?,11-,12-,13-,14?,15?,16?,17?/m1/s1

InChI key

XGCUCFKWVIWWNW-LTNYHXKASA-N

General description

Fusarenon X is a trichothecene mycotoxin isolated from Fusarium nivale.

Application

Fusarenon X may be used as a reference standard for the determination of fusarenon X in barley, wheat and corn samples by high-performance thin-layer chromatography (HPTLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 1 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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High-performance thin-layer chromatographic determination of deoxynivalenol, fusarenon-X, and nivalenol in barley, corn, and wheat.
Trucksess M W, et al.
Journal of Agricultural and Food Chemistry, 35(4), 445-448 (1987)
General pharmacological studies of fusarenon-X, a trichothecene mycotoxin from Fusarium species.
Matsuoka Y, et al.
Toxicology and Applied Pharmacology, 50(1), 87-94 (1979)
Margit Schollenberger et al.
International journal of food microbiology, 72(1-2), 85-89 (2002-02-15)
A total of 60 samples of wheat flour were collected during the first 6 months of 1999 from mills and food stores in an area in southwest Germany. Samples included whole-grain and two types of white flour with these three
C Maragos et al.
Food additives and contaminants, 23(8), 816-825 (2006-06-30)
Nivalenol is a mycotoxin produced by certain fungi that are pathogenic to important cereal crops, in particular maize, wheat, and barley. This toxin, 3alpha,4beta,7alpha,15-tetrahydroxy-12,13-epoxytrichothec-9-en-8-one, is found worldwide and is closely related to 4-deoxynivalenol (DON or vomitoxin), a mycotoxin associated with
Katsuhiro Miura et al.
Toxicology, 172(2), 103-112 (2002-03-08)
Fusarenon-X (FX), a trichothecene mycotoxin, is well known to be cytotoxic to mammalian cells. Our previous study revealed that FX induced apoptosis in mouse thymocytes both in vivo and in vitro. We investigated the mode of apoptosis induced by FX

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