SCC338
3dGRO Colon Intestinal Organoids, Age 19 (Prep ht-105-C)
Normal, Colon, Age: 19, Male, Mutation: None
Synonym(s):
colon organoids
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About This Item
NACRES:
NA.21
UNSPSC Code:
41106509
Pricing and availability is not currently available.
Quality Segment
biological source
human colon
packaging
vial of >1500 viable organoids cells
manufacturer/tradename
Millipore
gender
male
growth mode
N/A
technique(s)
cell culture: suitable
application(s)
3D cell culture
control
colon
relevant disease(s)
(Normal)
shipped in
liquid nitrogen
storage temp.
−196°C
Application
- Viability: >1500 viable organoids/vial
- Organoid Growth: Pass
- Cells are tested negative for infectious diseases by a Human Essential CLEAR panel by Charles River Animal Diagnostic Services.
- Mycoplasma Contamination: Negative
- STR Profile: Pass
Patient derived organoids (PDOs) are novel in vitro 3D cell models that preserve original tissue physiology and molecular pathology, thus representing a clinically-relevant alternative to traditional 2D cell lines and an effective tool to refine and reduce animal models. PDOs can be derived from adult patient biopsies or resected tissues containing native LGR5+ stem cell populations and cultured within an ECM-rich substrate using specialized organoid media such as L-WRN conditioned media. Adult tissue derived organoids are phenotypically and genetically stable in long term culture, presenting more mature phenotypes compared to iPSC-derived organoids. Importantly, PDOs have shown to be able to predict patient clinical responses to chemotherapeutics.We are now offering a comprehensive biobank of highly characterized tissue-derived human gastrointestinal organoids from normal and diseased patients. The intestinal organoid biobank contains over 50 highly characterized intestinal organoids from both normal and diseased patients derived from multiple regions of the digestive systems including small intestine (duodenum, ileum), stomach, rectum and colon.Cell Line Characteristics• Sex: Male• Age: 19 Years • Organ: Colon• Disease: Normal
Features and Benefits
Cryopreserved patient derived gastrointestinal organoids (PDOs)
Preparation Note
Store in liquid nitrogen. The organoids can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.
Legal Information
3dGRO® is a trademark of Merck KGaA, Darmstadt, Germany.3dGRO® organoids were derived utilizing HUB Organoid Technology.Subject to local law, this product is intended to be sold for internal in vitro research use only subject to terms and conditions found here: www.sigmaaldrich.com/pdouse. This product may not be re-engineered or copied; used to make derivatives or modifications; used to develop, test, or manufacture a commercial product; used as a component in a commercial product; resold or licensed; used in any clinical applications or trials; or used in humans. A license or limited commercial use agreement is required for use by any for-profit entity, use in services, and use in sponsored academic research. For information regarding any such use, please contact organoids@milliporesigma.com.
3dGRO is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Subject to local law, this product is intended to be sold for internal in vitro research use only subject to terms and conditions found here: www.sigmaaldrich.com/pdouse. This product may not be: re-engineered or copied; used to make derivatives or modifications; used to develop, test, or manufacturer a commercial product; used as a component in a commercial product; resold or licensed; used in any clinical applications or trials; or used in humans. A license or limited commercial use agreement is required for use by any for-profit entity, use in services, and use in sponsored academic research. For information regarding any such use, please contact organoids@milliporesigma.com
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This Item | |||
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| description Normal, Colon, Age: 19, Male, Mutation: None | description Normal, Colon, Age: 53, Female, Mutation: None | description Normal, Colon, Age: 51, Male, Mutation: None | description Normal, Colon Descending, Age: 59, Female, Mutation: None |
| technique(s) cell culture: suitable | technique(s) cell culture: suitable | technique(s) cell culture: suitable | technique(s) cell culture: suitable |
| relevant disease(s) (Normal) | relevant disease(s) (Normal) | relevant disease(s) (Normal) | relevant disease(s) - |
| application(s) 3D cell culture | application(s) 3D cell culture | application(s) 3D cell culture | application(s) 3D cell culture |
| biological source human colon | biological source human colon | biological source human colon | biological source human |
| storage temp. −196°C | storage temp. −196°C | storage temp. −196°C | storage temp. −196°C |
| packaging vial of >1500 viable organoids cells | packaging vial of >1500 viable organoids cells | packaging vial of >1500 viable organoids cells | packaging vial of >1500 viable organoids cells |
Storage Class
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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