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Anti-Ago3 Antibody, clone 4B1-F6

Name: Anti-Ago3 Antibody, clone 4B1-F6
Brand: MM
Price: 10500 CZK
Availability: InStock

clone 4B1-F6, from mouse

Synonym(s):

eIF-2C 3, eIF2C 3, FLJ12765, MGC86946

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Size/SKU	Availability	Price
100 μg	Estimated to ship onJune 04, 2026fromAreál Kühne+Nagel spol. s r.o.	CZK 10,500.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

4B1-F6, monoclonal

Application:

ICC, IP

Citations:

CZK 10,500.00

Estimated to ship onJune 04, 2026Details

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Properties

biological source

mouse

Quality Segment

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

4B1-F6, monoclonal

species reactivity

human

technique(s)

immunocytochemistry: suitable, immunoprecipitation (IP): suitable

isotype

IgG2aκ

NCBI accession no.

NP_079128

UniProt accession no.

Q9H9G7

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... AGO3(192669)

Description

General description

Eukaryotic translation initiation factor 2C 3, Ago3, belongs to the argonaute family and contains 1 PAZ and 1 Piwi domain.

Ago3 is indicated to play a role in the RNA interference (RNAi) pathway, which is important for heterochromatin formation and accurate chromosome segregation. Unlike Ago1 and Ago2, Ago3 and AG04 do not possess the ability to dissociate miRNA duplexes in a minimal in vitro system. Re-introduction of any Ago variant into embyronic (ES) cells deficient for expression of all four Ago variants will rescue miRNA silencing defects and reduce apoptosis.

96 kDa calculated.

Immunogen

Recombinant protein corresponding to human Ago3.

Application

Anti-Ago3 Antibody, clone 4B1-F6 is a Mouse Monoclonal Antibody for detection of Ago3 also known as eIF-2C 3, eIF2C 3, FLJ12765, MGC86946 & has been validated in ICC & IP.

Immunoprecipitation Analysis: A representative lot was used by an independent laboratory in HeLa cells. (Azuma-Mukai, A., et al. (2008). Proc Natl Acad Sci. USA. 105(23):7964-7969.)

Physical form

Format: Purified

Analysis Note

Evaluated by Immunocytochemistry in HeLa cells.

Immunocytochemistry Analysis: A 1:500 dilution of this antibody detected Ago3 in HeLa cells.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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This Item	SAB4200724	MABE56	MABE253
Sigma-Aldrich MABE144 Anti-Ago3 Antibody, clone 4B1-F6	Sigma-Aldrich SAB4200724 Anti-AGO2 antibody, Mouse monoclonal	Sigma-Aldrich MABE56 Anti-pan Ago Antibody, clone 2A8	Sigma-Aldrich MABE253 Anti-Ago2 Antibody, clone 11A9
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form purified immunoglobulin	antibody form purified from hybridoma cell culture	antibody form purified immunoglobulin	antibody form purified antibody
biological source mouse	biological source mouse	biological source mouse	biological source rat
Gene Information human ... AGO3(192669)	Gene Information human ... AGO2(27161)	Gene Information human ... AGO1(26523)	Gene Information human ... AGO2(27161)
species reactivity human	species reactivity human	species reactivity human	species reactivity human
clone 4B1-F6, monoclonal	clone AGO2-10, monoclonal	clone 2A8, monoclonal	clone 11A9, monoclonal

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c