MAB5416

Anti-Glutamate Receptor 3 Antibody, clone 3B3

clone 3B3, Chemicon^®, from mouse

• Synonym(s): AMPA-selective glutamate receptor 3, Glutamate receptor ionotropic, AMPA 3, glutamate receptor 3, glutamate receptor C, glutamate receptor subunit 3, glutamate receptor, ionotrophic, AMPA 3
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: 3B3, monoclonal
• Application: ICC, IHC (p), WB
• Citations: 40

Properties

• biological source: mouse
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: 3B3, monoclonal
• species reactivity: monkey, mouse, human
• species reactivity (predicted by homology): rat
• manufacturer/tradename: Chemicon^®
• technique(s): immunocytochemistry: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, western blot: suitable
• isotype: IgG1κ
• NCBI accession no.: NM_000840.2
• UniProt accession no.: P42263
• shipped in: dry ice
• target post-translational modification: unmodified
• Gene Information: human ... GRIA3(2892)

Description

General description

AMPA receptors mediate fast synaptic current at most excitatory synapses, with stoichiometry characterized by subtype composition.There are four types of AMPA selective GluR subunits (GluR1, GluR2, GluR3 and GluR4). Tetrameric or pentameric combinations of different subunits contributes to the functional diversity of AMPA receptors. The insertion or removal of GluR1/GluR4 oligomeric channels from postsynaptic membranes appears to be LTP/LTD activity dependent while GluR2/GluR3 oligomers are continuously cycling. Millipore’s anti-GluR2/3 antibody is useful for localizing expression of GluR2/GluR3 receptor assemblies in the PSD.

~ 110 kDa

Immunogen

Fusion protein, N-terminus of GluR3

Application

Anti-Glutamate Receptor 3 Antibody, clone 3B3 is an antibody against Glutamate Receptor 3 for use in WB, IC, IH, IH(P).

Immunohistochemistry: A previous lot of this antibody was used in IH.

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Reacts with Glutamate Receptor 3 (GluR3). No cross reactivity with GluR2.

Physical form

Format: Purified

Liquid in PBS. Contains no preservative.

Analysis Note

Control
Brain

Hippocampal tissue

Western Blot Analysis: A previous lot of this antibody was used in WB.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable