FCMAB306P

Milli-Mark Anti-Human-Nuclei-PE Antibody, clone 235-1

clone 235-1, Milli-Mark^®, from mouse

• Synonym(s): HuNu
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: PE
• Clone: 235-1, monoclonal
• Application: FACS
• Citations: -

Properties

• biological source: mouse
• conjugate: PE
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: 235-1, monoclonal
• species reactivity (predicted by homology): human (based on 100% sequence homology)
• manufacturer/tradename: Milli-Mark^®
• technique(s): flow cytometry: suitable
• isotype: IgG1κ
• shipped in: wet ice
• target post-translational modification: unmodified

Description

General description

Stem-cell and fetal-cell replacement therapies for many diseases have proven to be very hopeful. Human nuclei antibodies are very important histological and cytological markers for identifying human cells. The use of human nuclei and C-peptide to force differentiation of human mesenchymal stem cells into insulin-producing cells to treat diabetes mellitus in mice has been successful. Human nuclei cells have also been associated with using stem-cell treatment in spinal cord injuries in canines.

Application

Detect Human-Nuclei using this Milli-Mark Anti-Human-Nuclei-PE Antibody, clone 235-1 validated for use in FC.

Research Category
Stem Cell Research

Research Sub Category
Neural Stem Cells

Biochem/physiol Actions

Stains nuclei of all human cell types giving a diffuse nuclear staining pattern. Chromosomes are negatively stained in metaphase cells. Also stains nuclei from primate (Sanchez-Pernaute, 2005). The antibody does not react with nuclei from mouse or rat.

Physical form

Protein A purified

Purified mouse monoclonal IgG1κ conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Preparation Note

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Analysis Note

Control
Jurkat cells.

Evaluated by flow cytometry using Jurkat cells.

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: WGK 2