8.52372

Fmoc-selenomethionine

Novabiochem^®

• Synonym(s): Fmoc-selenomethionine, N-Fmoc-L-amino-4-(methylselanyl)butanoic acid
• Empirical Formula (Hill Notation): C₂₀H₂₁NO₄Se
• CAS Number: 1217852-49-7
• Molecular Weight: 418.35
• UNSPSC Code: 12352209

Properties

• Quality Segment: 200
• product line: Novabiochem^®
• form: powder
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• application(s): peptide synthesis
• functional group: Fmoc
• storage temp.: 2-8°C
• InChI: 1S/C20H21NO4Se/c1-26-11-10-18(19(22)23)21-20(24)25-12-17-15-8-4-2-6-13(15)14-7-3-5-9-16(14)17/h2-9,17-18H,10-12H2,1H3,(H,21,24)(H,22,23)/t18-/m0/s1
• InChI key: MOIJGLAOGAWHTN-SFHVURJKSA-N

Description

General description

Fmoc-selenomethionine can be introduced under standard conditions. Any selenoxide formed during synthesis can be easily reduced back to selenide by treatment with β-mercaptoethanol. Introduction of selenium can help facilitate solid phase and solution structural determination and the study of peptide-protein interactions ^[1].

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Literature references

^[1] L. Moroder (2005) J. Pept.Sci., 11, 187.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• WGK: WGK 3
• Flash Point (°C): Not applicable
• Pictograms: GHS06,GHS08,GHS09
• Signal Word: Danger
• Hazard Codes: H301 + H331,H315,H335,H373,H410
• Precautionary Statements: P260 - P273 - P301 + P310 - P302 + P352 - P304 + P340 + P311 - P314
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - STOT RE 2 - STOT SE 3
• Target Organs: Respiratory system
• Flash Point (°F): Not applicable
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects