8.52212

Fmoc-Met(O₂)-OH

Novabiochem^®

• Synonym(s): Fmoc-Met(O₂)-OH, N-α-Fmoc-L-methionine-sulfone
• Empirical Formula (Hill Notation): C₂₀H₂₁NO₆S
• CAS Number: 163437-14-7
• Molecular Weight: 403.45
• MDL number: MFCD00153361
• UNSPSC Code: 12352209
• NACRES: NA.22

Properties

• Quality Segment: 200
• product line: Novabiochem^®
• assay: ≥90.0% (acidimetric), ≥97.0% (HPLC), ≥98% (TLC)
• form: powder
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• application(s): peptide synthesis
• functional group: Fmoc
• storage temp.: 2-30°C
• SMILES string: [S](=O)(=O)(CC[C@H](NC(=O)OCC1c2c(cccc2)c3c1cccc3)C(=O)O)C
• InChI: 1S/C20H21NO6S/c1-28(25,26)11-10-18(19(22)23)21-20(24)27-12-17-15-8-4-2-6-13(15)14-7-3-5-9-16(14)17/h2-9,17-18H,10-12H2,1H3,(H,21,24)(H,22,23)/t18-/m0/s1
• InChI key: KJLKPACOHZKRFM-SFHVURJKSA-N

Description

General description

Standard building block for introduction of methionine sulfone residues by Fmoc SPPS.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (TLC(011C)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 90.0 %
Water (K. F.): ≤ 3.0 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Other Notes

Replaces: 04-12-1113

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable