When using Dabcyl for coupling reactions, it is often necessary to activate it with coupling agents or activators to facilitate the formation of the desired amide bond. Commonly used coupling reagents include EDC (1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide), DCC (Dicyclohexylcarbodiimide), and HOBt (hydroxybenzotriazole).
8.51022
Dabcyl-OSu
Novabiochem®
Synonym(s):
Dabcyl-OSu, N-(4-[4Æ-(Dimethylamino)phenylazo]benzoyloxy)succinimide
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| Size/SKU | Availability | Price |
|---|---|---|
1 g | Please contact Customer Service for Availability | CZK 10,000.00 |
About This Item
Empirical Formula (Hill Notation):
C19H18N4O4
CAS Number:
Molecular Weight:
366.37
UNSPSC Code:
12352108
NACRES:
NA.22
MDL number:
Quality Segment
product line
Novabiochem®
assay
≥98.0% (HPLC)
form
powder
reaction suitability
reagent type: fluorescent-labelling reagent
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
storage temp.
15-25°C
SMILES string
N3(C(=O)CCC3=O)OC(=O)c1ccc(cc1)N=Nc2ccc(cc2)N(C)C
InChI
1S/C19H18N4O4/c1-22(2)16-9-7-15(8-10-16)21-20-14-5-3-13(4-6-14)19(26)27-23-17(24)11-12-18(23)25/h3-10H,11-12H2,1-2H3
InChI key
IBOVDNBDQHYNJI-UHFFFAOYSA-N
General description
Pre-activated derivative for the introduction of the Dabcyl group during SPPS. The Dabcyl group quenches the fluorescence of EDANS, Mca, TET, JOE, FAM fluorophores, making it an extremely useful tool for the synthesis of fluorescence-quenched peptide substrates.
Associated Protocols and Technical Articles
Chromogenic Labeling of Synthetic Peptides
Associated Protocols and Technical Articles
Chromogenic Labeling of Synthetic Peptides
Analysis Note
Color (visual): red
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(011A)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
To see the solvent systems used for TLC of Novabiochem® products please click here.
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(011A)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
To see the solvent systems used for TLC of Novabiochem® products please click here.
Other Notes
Replaces: 01-63-0105
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
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This Item | |||
|---|---|---|---|
| reaction suitability reagent type: fluorescent-labelling reagent | reaction suitability - | reaction suitability - | reaction suitability - |
| product line Novabiochem® | product line Novabiochem® | product line Novabiochem® | product line Novabiochem® |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| application(s) peptide synthesis | application(s) peptide synthesis | application(s) peptide synthesis | application(s) peptide synthesis |
| storage temp. 15-25°C | storage temp. 15-25°C | storage temp. 2-8°C | storage temp. 2-8°C |
| form powder | form powder | form powder | form powder |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Per un coupling il Dabcyl ha bisogno di essere attivato con gli attivanti o va messo solo Dabcyl e DIPEA?
1 answer-
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