8.00683

Succinic anhydride

for synthesis

• Synonym(s): Succinic anhydride
• Empirical Formula (Hill Notation): C₄H₄O₃
• CAS Number: 108-30-5
• Molecular Weight: 100.07
• MDL number: MFCD00005525
• UNSPSC Code: 12352115
• EC Index Number: 203-570-0
• NACRES: NA.22

Properties

• vapor pressure: 1.3 hPa ( 92 °C)
• Quality Level: 200
• form: crystals
• autoignition temp.: 480 °C
• potency: 1510 mg/kg LD₅₀, oral (Rat)
• pH: 2.7 (10 g/L in H₂O)
• bp: 261 °C/1013 hPa
• mp: 116-120 °C
• transition temp: flash point 157 °C
• solubility: 62.9 g/L (Hydrolysis)
• density: 1.23 g/cm³ at 20 °C
• bulk density: 550‑600 kg/m³
• storage temp.: 2-30°C
• InChI: 1S/C4H4O3/c5-3-1-2-4(6)7-3/h1-2H2
• InChI key: RINCXYDBBGOEEQ-UHFFFAOYSA-N

Description

Application

• Enhanced antimicrobial fibers: Succinic anhydride is utilized in the conjugation of chitosan with Harakeke and Hemp fibers to produce antimicrobial fibers, which significantly increase their utility in medical and hygiene products (Barker et al., 2024).
• Antitumor diterpenoids: Succinic anhydride is integral to synthesizing new clerodane diterpenoids from Callicarpa pseudorubella, which show potential antitumor proliferative activity, expanding its applications in cancer research (Pan et al., 2024).
• Nanogel delivery systems: It plays a role in developing nanogel delivery systems for cationic peptides, enhancing the delivery of therapeutic agents and showcasing its versatility in pharmaceutical delivery systems (Mørck Nielsen et al., 2024).

Analysis Note

Assay (morpholine method): ≥ 98,0 %(m)
Identity (IR): conforms
Melting range (lower value): ≥ 116 °C
Melting range (upper value): ≤ 120 °C

Safety Information

• Pictograms: GHS05,GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H302 - H314 - H317 - H334
• Precautionary Statements: P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1
• Storage Class Code: 8A - Combustible, corrosive hazardous materials
• WGK: WGK 1
• Flash Point(F): 314.6 °F
• Flash Point(C): 157 °C