539604

PKC_η Pseudosubstrate Inhibitor, Myristoylated

The PKC_η Pseudosubstrate Inhibitor, Myristoylated controls the biological activity of PKC_η. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• Synonym(s): PKC_η Pseudosubstrate Inhibitor, Myristoylated, Myr-TRKRQRAMRRRVHQING-OH, Protein Kinase C _η Pseudosubstrate Inhibitor, Myristoylated
• Empirical Formula (Hill Notation): C₁₀₁H₁₈₅N₄₁O₂₃S
• Molecular Weight: 2373.88
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥95% (HPLC)
• form: lyophilized solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic)
• solubility: water: 1 mg/mL
• shipped in: ambient
• storage temp.: −20°C

Description

General description

A cell-permeable, reversible, substrate competitive, and pseudosubstrate inhibitor of the protein kinase C_η isozyme. Useful for studies of PKC_η function in intact cells.

Biochem/physiol Actions

Cell permeable: yes

Primary Target
PKCν

Product competes with ATP.

Reversible: yes

Packaging

Yes

Warning

Toxicity: Standard Handling (A)

Sequence

Myr-Thr-Arg-Lys-Arg-Gln-Arg-Ala-Met-Arg-Arg-Arg-Val-His-Gln-Ile-Asn-Gly-OH

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Osada, S., et al. 1992. Mol. Cell Biol.12, 3930.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable