457250

Methylene Blue

guanylate cyclase inhibitor, solid

• Synonym(s): Methylthioninium chloride, 3,7- bis(Dimethylamino)phenothiazin-5-ium Chloride, 3,7-bis(Dimethylamino)phenothiazin-5-ium Chloride, Methylene blue
• Empirical Formula (Hill Notation): C₁₆H₁₈ClN₃S
• CAS Number: 61-73-4
• Molecular Weight: 319.85
• UNSPSC Code: 12171500
• NACRES: NA.77
• MDL number: MFCD00012111
• Form: solid
• Storage condition: OK to freeze

Properties

• Product Name: Methylene Blue, Inhibitor of soluble guanylate cyclase.
• Quality Segment: 100
• description: Merck USA index - 14, 6060
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: dark green
• solubility: water: 4 mg/mL
• shipped in: ambient
• storage temp.: 10-30°C
• SMILES string: [s]1c2c(nc3c1cc(cc3)N(C)C)cc[c](c2)=[N+](C)C.[Cl-]
• InChI: 1S/C16H18N3S.ClH/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;/h5-10H,1-4H3;1H/q+1;/p-1
• InChI key: CXKWCBBOMKCUKX-UHFFFAOYSA-M

Description

General description

Inhibitor of soluble guanylate cyclase. Organic spin-trap agent that forms stable adducts with oxygen free radicals in solution; biological staining agent. Dye content: ≥85%.

Other Notes

Kannan, M.S., and Johnson, D.E. 1995. Life Sci.56, 2229.
Hedrum, A., et al. 1994. Biotechniques17, 118.
Lim, C.S., and Hunt, C.A. 1994. Biotechniques17, 626.
Yezzi, M.J., et al. 1994. J. Immunol.152, 3064.
Mayer, B., et al. 1993. Biochem. Pharmacol.45, 367.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk: WGK 2