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444264

MMP Inhibitor III

The MMP Inhibitor III, also referenced under CAS 927827-98-3, controls the biological activity of MMP. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Synonym(s):

MMP Inhibitor III

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1 mg

Available to ship TODAYfromAreál Kühne+Nagel spol. s r.o.

CZK 4,240.00

About This Item

Empirical Formula (Hill Notation):
C19H29N3O4
CAS Number:
927827-98-3
Molecular Weight:
363.45
MDL number:
MFCD00001382
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥90% (TLC)
Form:
lyophilized solid
Storage condition:
OK to freeze, desiccated

CZK 4,240.00

Available to ship TODAYDetails

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Quality Segment

100

assay

≥90% (TLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated

color

off-white

solubility

DMSO: 5 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

A homophenylalanine-hydroxamic acid based broad-spectrum cell-permeable, reversible inhibitor of matrix metalloproteinases (supplied as a racemic mixture). Inhibits MMP-1 (IC50 = 7.4 nM), MMP-2 (IC50 = 2.3 nM), MMP-3 (IC50 = 135 nM), MMP-7 (IC50 = 10-100 nM), and MMP-13 (IC50 = 1-10 nM).

Biochem/physiol Actions

Cell permeable: yes
Primary Target
MMP-1
Product does not compete with ATP.
Reversible: yes
Target IC50: 7.4 nM, 2.3 nM, 135 nM, 10-100 nM, 1-10 nM, against MMP-1, MMP-2, MMP-3, MMP-7, and MMP-13, respectively

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months (-20°C).

Other Notes

Covington, M.D., et al. 2006, Am. J. Physiol. Renal. Physiol.290, F43.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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This Item
444218444225444288
MMP Inhibitor III The MMP Inhibitor III, also referenced under CAS 927827-98-3, controls the biological activity of MMP. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Sigma-Aldrich

444264

MMP Inhibitor III

MMP-3 Inhibitor I The MMP-3 Inhibitor I controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Sigma-Aldrich

444218

MMP-3 Inhibitor I

MMP-3 Inhibitor II The MMP-3 Inhibitor II, also referenced under CAS 161314-17-6, controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Sigma-Aldrich

444225

MMP-3 Inhibitor II

MMP-2 Inhibitor III The MMP-2 Inhibitor III, also referenced under CAS 704888-90-4, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Sigma-Aldrich

444288

MMP-2 Inhibitor III

form

lyophilized solid

form

solid

form

solid

form

solid

assay

≥90% (TLC)

assay

≥90% (HPLC)

assay

≥98% (TLC)

assay

≥95% (HPLC)

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

10-30°C

storage temp.

2-8°C

storage condition

OK to freeze, desiccated

storage condition

OK to freeze, desiccated (hygroscopic)

storage condition

OK to freeze

storage condition

OK to freeze, protect from light

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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