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230950

Ciglitazone

A potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective PPARγ agonist (EC50 = 3 µM).

Synonym(s):

Ciglitazone, (±)-5-[4-(1-Methylcyclohexylmethoxy)benzyl]thiazolidine-2,4-dione, PPAR Agonist II, PPARγ Agonist I

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Size/SKUAvailabilityPrice
5 mg

Estimated to ship onJune 03, 2026fromAreál Kühne+Nagel spol. s r.o.

CZK 4,380.00

About This Item

Empirical Formula (Hill Notation):
C18H23NO3S
CAS Number:
74772-77-3
Molecular Weight:
333.45
NACRES:
NA.77
UNSPSC Code:
12352200
MDL number:
MFCD00865499
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
OK to freeze

CZK 4,380.00

Estimated to ship onJune 03, 2026Details

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Quality Segment

100

description

RTECS - XJ5813700

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

tan

solubility

DMSO: ≥25 mg/mL, ethanol: ≥25 mg/mL

shipped in

ambient

storage temp.

2-8°C

InChI

1S/C18H23NO3S/c1-18(9-3-2-4-10-18)12-22-14-7-5-13(6-8-14)11-15-16(20)19-17(21)23-15/h5-8,15H,2-4,9-12H2,1H3,(H,19,20,21)

InChI key

YZFWTZACSRHJQD-UHFFFAOYSA-N

General description

A potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 3 µM).

Biochem/physiol Actions

Cell permeable: no
EC50 = 3 µM as PPARγ agonist
Primary Target
Selective PPARγ agonist
Product does not compete with ATP.
Reversible: no

Preparation Note

Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Jha, R.J. 1999. Clin. Exp. Hypertens. 21, 157.
Xin, X., et al. 1999. J. Biol. Chem. 274, 9116.
Lohrke, B., et al. 1998. J. Endocrinol. 159, 429.
Willson, T.M., et al. 1996. J. Med. Chem. 39, 665.
Cantello, B.C., et al. 1994. J. Med. Chem. 37, 3977.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

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This Item
C3974371721528108
Ciglitazone A potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective PPARγ agonist (EC50 = 3 µM).

Sigma-Aldrich

230950

Ciglitazone

Ciglitizone ≥98% (HPLC)

Sigma-Aldrich

C3974

Ciglitizone

GPR40 Agonist II The GPR40 Agonist II controls the biological activity of GPR40. This small molecule/inhibitor is primarily used for Biochemicals applications.

Sigma-Aldrich

371721

GPR40 Agonist II

PI 3-Kγ Inhibitor II The PI 3-Kγ Inhibitor II, also referenced under CAS 648449-76-7, controls the biological activity of PI 3-Kγ. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Sigma-Aldrich

528108

PI 3-Kγ Inhibitor II

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

solid

form

powder

form

powder

form

solid

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: ≥25 mg/mL, ethanol: ≥25 mg/mL

solubility

-

solubility

DMSO: 100 mg/mL, clear, colorless

solubility

DMSO: 10 mg/mL, ethanol: 5 mg/mL

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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