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219445

Cdk2 Inhibitor II

The Cdk2 Inhibitor II, also referenced under CAS 222035-13-4, controls the biological activity of Cdk2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Synonym(s):

Cdk2 Inhibitor II, Compound 3

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About This Item

Empirical Formula (Hill Notation):
C14H11BrN4O3S
CAS Number:
Molecular Weight:
395.23
UNSPSC Code:
12352200
Assay:
≥95% (sum of two isomers, HPLC)
Form:
solid
Storage condition:
OK to freeze, protect from light


Quality Segment

assay

≥95% (sum of two isomers, HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

yellow

solubility

DMSO: 5 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

A cell-permeable, reversible, ATP-competitive, potent and selective inhibitor of Cdk2 (IC50 = 60 nM).

Biochem/physiol Actions

Cell permeable: yes
Primary Target
CDK2
Product competes with ATP.
Reversible: yes
Target IC50: 60 nM against Cdk2

Packaging

Packaged under inert gas

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Davis, S.T., et al. 2001. Science291, 134.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)


Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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