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203392

(+)-Blebbistatin

The inactive enantiomer of (±)-Blebbistatin.

Synonym(s):

(+)-Blebbistatin

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Size/SKUAvailabilityPrice
1 mg

Estimated to ship TODAYfromAreál Kühne+Nagel spol. s r.o.

CZK 4,270.00

About This Item

Empirical Formula (Hill Notation):
C18H16N2O2
CAS Number:
1177356-70-5
Molecular Weight:
292.33
MDL number:
MFCD08460906
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
OK to freeze, protect from light

CZK 4,270.00

Estimated to ship TODAYDetails

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Quality Segment

100

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

yellow

solubility

methanol: 1.5 mg/mL, 100% DMSO: 100 mg/mL, 90% DMSO: 75 mg/mL

shipped in

wet ice

storage temp.

−20°C

SMILES string

N2(CC[C@]3(C2=Nc4c(cc(cc4)C)C3=O)O)c1ccccc1

InChI

1S/C18H16N2O2/c1-12-7-8-15-14(11-12)16(21)18(22)9-10-20(17(18)19-15)13-5-3-2-4-6-13/h2-8,11,22H,9-10H2,1H3/t18-/m0/s1

InChI key

LZAXPYOBKSJSEX-SFHVURJKSA-N

General description

The inactive enantiomer of (±)-Blebbistatin (Cat. No. 203390). Useful as a negative control for the active enantiomer (Cat. No. 203391).

Biochem/physiol Actions

Cell permeable: no
Primary Target
Inactive enantiomer of (±)-Blebbistatin
Product does not compete with ATP.
Reversible: no

Packaging

Packaged under inert gas

Preparation Note

Following reconstitution in methanol, aliquot and freeze (-20°C). Stock solutions in 90% DMSO or methanol are stable for up to 1 month at -20°C. Stock solutions in 100% DMSO are unstable; reconstitute just prior to use.

Other Notes

Shu, S., et al. 2005. Proc. Natl. Acad. Sci. USA102, 1472.
Jacobelli, J., et al. 2004. Nat. Immunol.5, 531.
Kovacs, M., et al. 2004. J. Biol. Chem.279, 35557.
Straight, A.F., et al. 2003. Science299, 1743.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

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This Item
203391203390527455
(+)-Blebbistatin The inactive enantiomer of (±)-Blebbistatin.

Sigma-Aldrich

203392

(+)-Blebbistatin

(-)-Blebbistatin The active enantiomer of (±)-Blebbistatin that accounts for the inhibitory activity towards ATPase and myosin II-dependent cellular processes.

Sigma-Aldrich

203391

(-)-Blebbistatin

(±)-Blebbistatin (±)-Blebbistatin, CAS 674289-55-5, is a cell-permeable, selective, and reversible inhibitor of nonmuscle myosin II. Blocks cell blebbing and disrupts cell migration & cytoKinesis in vertebrate cells.

Sigma-Aldrich

203390

(±)-Blebbistatin

PKR Inhibitor, Negative Control The PKR Inhibitor, Negative Control, also referenced under CAS 852547-30-9, controls the biological activity of PKR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Sigma-Aldrich

527455

PKR Inhibitor, Negative Control

form

solid

form

solid

form

solid

form

solid

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥97% (HPLC)

assay

≥95% (sum of two isomers, HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, protect from light

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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