1.24541

Nicotinamide adenine dinucleotide phosphate disodium salt

pH 3.7-4.2 (10 mg/mL in water), ≥95.0% dry basis (enzymatic)

• Synonym(s): Nicotinamide adenine dinucleotide phosphate disodium salt, NADP disodium salt
• Empirical Formula (Hill Notation): C₂₁H₂₇N₇Na₂O₁₇P₃
• CAS Number: 24292-60-2
• Molecular Weight: 788.38
• UNSPSC Code: 12352107
• EC Index Number: 246-129-8
• NACRES: NA.21
• MDL number: MFCD00065390
• Assay: ≥95.0% dry basis (enzymatic)
• Form: solid
• Storage temp.: 2-8°C

Properties

• Quality Segment: 100
• assay: ≥95.0% dry basis (enzymatic)
• form: solid
• pH: 3.7-4.2 (10 mg/mL in water)
• storage temp.: 2-8°C
• SMILES string: [Na].[Na].[P](=O)([O-])(O[P](=O)(OC[C@H]3O[C@H]([C@@H]([C@@H]3O)O[P](=O)(O)O)[n]4c5ncnc(c5nc4)N)O)OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)[n+]2cc(ccc2)C(=O)N
• InChI: 1S/C21H28N7O17P3.2Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39)
• InChI key: WINXVPJGUQYDJA-WUEGHLCSSA-N

Description

General description

for biochemistry NADP-Na₂

Application

• Biochemical and molecular modulation of CCl4-induced peripheral and central damage by Tilia americana var. mexicana extracts.: Investigates the protective biochemical pathways enhanced by NADP, addressing oxidative stress and tissue damage in clinical settings, suggesting therapeutic potentials in pharmacology (Coballase-Urrutia et al., 2017).


• Selective Irreversible Inhibition of Neuronal and Inducible Nitric-oxide Synthase in the Combined Presence of Hydrogen Sulfide and Nitric Oxide.: Discusses the interaction of NADP in complex biochemical pathways influencing enzymatic activity, important for understanding cellular signaling and potential drug targets (Heine et al., 2015).


• Treatment with n-3 polyunsaturated fatty acids reverses endothelial dysfunction and oxidative stress in experimental menopause.: This research outlines the critical roles of NADP in managing oxidative stress and cellular health, showcasing its implications in dietary supplements and therapeutic interventions (Gortan Cappellari et al., 2013).

Analysis Note

Assay (enzymatically; calculated on solvent-free substance): ≥ 95 %
Identity (IR-spectrum): passes test
pH (10 mg/ml; water): 3.7 - 4.2
UV-Absorption (360 nm; 10 mg/ml; water): ≤ 0.20
Spec. Absorptivity A 1%/1cm (260 nm; 0.01 g/l; buffer pH 7.0; calculated on solvent-free substance): 220 - 240
Methanol (GC): ≤ 3.0 %
Water (according to Karl Fischer): ≤ 6.0 %

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable